Removing exogenous information using pedigree data

Amador, Carmen; Toro Ibañez, Miguel Angel y Fernandez, Jesus (2011). Removing exogenous information using pedigree data. "Conservation Genetics", v. 12 (n. 6); pp. 1565-1573. ISSN 1566-0621.


Título: Removing exogenous information using pedigree data
  • Amador, Carmen
  • Toro Ibañez, Miguel Angel
  • Fernandez, Jesus
Tipo de Documento: Artículo
Título de Revista/Publicación: Conservation Genetics
Fecha: Diciembre 2011
Volumen: 12
Escuela: E.T.S.I. Agrónomos (UPM) [antigua denominación]
Departamento: Producción Animal [hasta 2014]
Licencias Creative Commons: Reconocimiento - Sin obra derivada - No comercial

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Management of certain populations requires the preservation of its pure genetic background. When, for different reasons, undesired alleles are introduced, the original genetic conformation must be recovered. The present study tested, through computer simulations, the power of recovery (the ability for removing the foreign information) from genealogical data. Simulated scenarios comprised different numbers of exogenous individuals taking partofthe founder population anddifferent numbers of unmanaged generations before the removal program started. Strategies were based on variables arising from classical pedigree analyses such as founders? contribution and partial coancestry. The ef?ciency of the different strategies was measured as the proportion of native genetic information remaining in the population. Consequences on the inbreeding and coancestry levels of the population were also evaluated. Minimisation of the exogenous founders? contributions was the most powerful method, removing the largest amount of genetic information in just one generation.However, as a side effect, it led to the highest values of inbreeding. Scenarios with a large amount of initial exogenous alleles (i.e. high percentage of non native founders), or many generations of mixing became very dif?cult to recover, pointing out the importance of being careful about introgression events in population

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ID de Registro: 11795
Identificador DC:
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Identificador DOI: 10.1007/s10592-011-0255-4
URL Oficial:
Depositado por: Memoria Investigacion
Depositado el: 03 Oct 2012 07:10
Ultima Modificación: 22 Sep 2014 10:51
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