Nonrigid Motion Compensation of Free Breathing Acquired Myocardial Perfusion Data

Wöllny, Gert and Kellman, Peter and Santos Lleo, Andres de and Ledesma Carbayo, María Jesús (2011). Nonrigid Motion Compensation of Free Breathing Acquired Myocardial Perfusion Data. In: "Bildverarbeitung für die Medizin 2011 (Algorithmen, Systeme, Anwendungen)", 20/03/2011 - 22/03/2011, Lübeck, Alemania.

Description

Title: Nonrigid Motion Compensation of Free Breathing Acquired Myocardial Perfusion Data
Author/s:
  • Wöllny, Gert
  • Kellman, Peter
  • Santos Lleo, Andres de
  • Ledesma Carbayo, María Jesús
Item Type: Presentation at Congress or Conference (Article)
Event Title: Bildverarbeitung für die Medizin 2011 (Algorithmen, Systeme, Anwendungen)
Event Dates: 20/03/2011 - 22/03/2011
Event Location: Lübeck, Alemania
Title of Book: Proceedings of Bildverarbeitung für die Medizin 2011 (Algorithmen, Systeme, Anwendungen)
Date: 2011
Subjects:
Faculty: E.T.S.I. Telecomunicación (UPM)
Department: Ingeniería Electrónica
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

In this work, we present a novel method to compensate the movement in images acquired during free breathing using first-pass gadolinium enhanced, myocardial perfusion magnetic resonance imaging (MRI). First, we use independent component analysis (ICA) to identify the optimal number of independent components (ICs) that separate the breathing motion from the intensity change induced by the contrast agent. Then, synthetic images are created by recombining the ICs, but other then in previously published work (Milles et al. 2008), we omit the component related to motion, and therefore, the resulting reference image series is free of motion. Motion compensation is then achieved by using a multi-pass non-rigid image registration scheme. We tested our method on 15 distinct image series (5 patients) consisting of 58 images each and we validated our method by comparing manually tracked intensity profiles of the myocardial sections to automatically generated ones before and after registration. The average correlation to the manually obtained curves before registration 0:89 0:11 was increased to 0:98 0:02

More information

Item ID: 12040
DC Identifier: http://oa.upm.es/12040/
OAI Identifier: oai:oa.upm.es:12040
Deposited by: Memoria Investigacion
Deposited on: 17 Sep 2012 11:16
Last Modified: 21 Apr 2016 11:12
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