Detection of growth-related QTLs in turbot (Scophtalmus maximux)

Sanchez Molano, Enrique; Cerna, Alex; Toro Ibañez, Miguel Angel; Bouza, Carmen; Hermida, Miguel; Pardo, Belen G.; Cabaleiro, Santiago; Fernandez, Jesus y Martinez, Paulino (2011). Detection of growth-related QTLs in turbot (Scophtalmus maximux). En: "62th Annual Meeting of the European Association for Animal Production", 29/08/2011 - 02/09/2011, Stavanger, Noruega. p. 45.

Descripción

Título: Detection of growth-related QTLs in turbot (Scophtalmus maximux)
Autor/es:
  • Sanchez Molano, Enrique
  • Cerna, Alex
  • Toro Ibañez, Miguel Angel
  • Bouza, Carmen
  • Hermida, Miguel
  • Pardo, Belen G.
  • Cabaleiro, Santiago
  • Fernandez, Jesus
  • Martinez, Paulino
Tipo de Documento: Ponencia en Congreso o Jornada (Artículo)
Título del Evento: 62th Annual Meeting of the European Association for Animal Production
Fechas del Evento: 29/08/2011 - 02/09/2011
Lugar del Evento: Stavanger, Noruega
Título del Libro: Proceedings of 62th Annual Meeting of the European Association for Animal Production
Fecha: 2011
Materias:
Escuela: E.T.S.I. Agrónomos (UPM) [antigua denominación]
Departamento: Producción Animal [hasta 2014]
Licencias Creative Commons: Reconocimiento - Sin obra derivada - No comercial

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Resumen

Background The turbot (Scophthalmus maximus) is a highly appreciated European aquaculture species. Growth related traits constitute the main goal of the ongoing genetic breeding programs of this species. The recent construction of a consensus linkage map in this species has allowed the selection of a panel of 100 homogeneously distributed markers covering the 26 linkage groups (LG) suitable for QTL search. In this study we addressed the detection of QTL with effect on body weight, length and Fulton's condition factor. Results Eight families from two genetic breeding programs comprising 814 individuals were used to search for growth related QTL using the panel of microsatellites available for QTL screening. Two different approaches, maximum likelihood and regression interval mapping, were used in order to search for QTL. Up to eleven significant QTL were detected with both methods in at least one family: four for weight on LGs 5, 14, 15 and 16; five for length on LGs 5, 6, 12, 14 and 15; and two for Fulton's condition factor on LGs 3 and 16. In these LGs an association analysis was performed to ascertain the microsatellite marker with the highest apparent effect on the trait, in order to test the possibility of using them for marker assisted selection. Conclusions The use of regression interval mapping and maximum likelihood methods for QTL detection provided consistent results in many cases, although the high variation observed for traits mean among families made it difficult to evaluate QTL effects. Finer mapping of detected QTL, looking for tightly linked markers to the causative mutation, and comparative genomics are suggested to deepen in the analysis of QTL in turbot so they can be applied in marker assisted selection programs.

Más información

ID de Registro: 12732
Identificador DC: http://oa.upm.es/12732/
Identificador OAI: oai:oa.upm.es:12732
URL Oficial: http://www.biomedcentral.com/1471-2164/12/473
Depositado por: Memoria Investigacion
Depositado el: 15 Nov 2012 09:58
Ultima Modificación: 21 Abr 2016 12:00
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