Changes in the Papez Circuit in early stages of Alzheimer's Disease

García-Polo, Pablo and Pajares, Gonzalo and Hernández Tamames, J.A. and Alfayate, E. and Frank, A. and Alvarez Linera, Juan (2011). Changes in the Papez Circuit in early stages of Alzheimer's Disease. In: "Global Alzheimer's Research Summit", 2011, Madrid.

Description

Title: Changes in the Papez Circuit in early stages of Alzheimer's Disease
Author/s:
  • García-Polo, Pablo
  • Pajares, Gonzalo
  • Hernández Tamames, J.A.
  • Alfayate, E.
  • Frank, A.
  • Alvarez Linera, Juan
Item Type: Presentation at Congress or Conference (Poster)
Event Title: Global Alzheimer's Research Summit
Event Dates: 2011
Event Location: Madrid
Title of Book: Global Alzheimer's Research Summit
Date: 2011
Subjects:
Faculty: Centro de Tecnología Biomédica (CTB) (UPM)
Department: Otro
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

Alzheimer's disease (AD) is the most common cause of demenMa. Neuronal and synapMc losses occur iniMally and predominantly in the medial temporal lobe structures including hippocampus, amygdala and thalamus, structures that belong to the Papez circuit. The integrity of the connecMons amongst them is essenMal for episodic memory, which is specifically impaired in AD. For this reason we have invesMgated the degeneraMon paRern of subcorMcal structures and its relaMon to early stages of AD, i.e. Mild CogniMve Impairment (MCI), both in the amnesic and mulMdomain types using structural magneMc resonance imaging (using a 3T GE scanner) and VBM‐DARTEL.

More information

Item ID: 13589
DC Identifier: http://oa.upm.es/13589/
OAI Identifier: oai:oa.upm.es:13589
Deposited by: Memoria Investigacion
Deposited on: 15 Jan 2013 09:46
Last Modified: 21 Apr 2016 12:55
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