The correlation between white-matter microstructure and the complexity of spontaneous brain activity: A difussion tensor imaging-MEG study

Fernandez Perez, Alberto and Rios Lagos, Marcos and Abasolo, Daniel and Hornero, Roberto and Alvarez Linera, Juan and Paúl, Nuria and Maestú, Fernando and Ortiz, Tomas (2011). The correlation between white-matter microstructure and the complexity of spontaneous brain activity: A difussion tensor imaging-MEG study. "NeuroImage", v. 57 (n. 4); pp. 1300-1307. ISSN 1053-8119. https://doi.org/10.1016/j.neuroimage.2011.05.079.

Description

Title: The correlation between white-matter microstructure and the complexity of spontaneous brain activity: A difussion tensor imaging-MEG study
Author/s:
  • Fernandez Perez, Alberto
  • Rios Lagos, Marcos
  • Abasolo, Daniel
  • Hornero, Roberto
  • Alvarez Linera, Juan
  • Paúl, Nuria
  • Maestú, Fernando
  • Ortiz, Tomas
Item Type: Article
Título de Revista/Publicación: NeuroImage
Date: August 2011
ISSN: 1053-8119
Volume: 57
Subjects:
Faculty: E.T.S.I. Telecomunicación (UPM)
Department: Tecnología Fotónica [hasta 2014]
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

The advent of new signal processing methods, such as non-linear analysis techniques, represents a new perspective which adds further value to brain signals' analysis. Particularly, Lempel–Ziv's Complexity (LZC) has proven to be useful in exploring the complexity of the brain electromagnetic activity. However, an important problem is the lack of knowledge about the physiological determinants of these measures. Although acorrelation between complexity and connectivity has been proposed, this hypothesis was never tested in vivo. Thus, the correlation between the microstructure of the anatomic connectivity and the functional complexity of the brain needs to be inspected. In this study we analyzed the correlation between LZC and fractional anisotropy (FA), a scalar quantity derived from diffusion tensors that is particularly useful as an estimate of the functional integrity of myelinated axonal fibers, in a group of sixteen healthy adults (all female, mean age 65.56 ± 6.06 years, intervals 58–82). Our results showed a positive correlation between FA and LZC scores in regions including clusters in the splenium of the corpus callosum, cingulum, parahipocampal regions and the sagittal stratum. This study supports the notion of a positive correlation between the functional complexity of the brain and the microstructure of its anatomical connectivity. Our investigation proved that a combination of neuroanatomical and neurophysiological techniques may shed some light on the underlying physiological determinants of brain's oscillations

More information

Item ID: 13659
DC Identifier: http://oa.upm.es/13659/
OAI Identifier: oai:oa.upm.es:13659
DOI: 10.1016/j.neuroimage.2011.05.079
Deposited by: Memoria Investigacion
Deposited on: 21 Nov 2012 10:01
Last Modified: 21 Apr 2016 12:59
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