Probabilistic reasoning with a bayesian DNA device based on strand displacement

Sainz de Murieta Fuentes, Iñaki and Rodríguez-Patón Aradas, Alfonso (2012). Probabilistic reasoning with a bayesian DNA device based on strand displacement. In: "DNA Computing and Molecular ProgrammingLecture Notes in Computer Science Volume 7433, 2012", 14/08/2012 - 17/08/2012, Aarhus, Dinamarca. ISBN 978-3-642-32207-5. pp. 110-122. https://doi.org/10.1007/978-3-642-32208-2_9.

Description

Title: Probabilistic reasoning with a bayesian DNA device based on strand displacement
Author/s:
  • Sainz de Murieta Fuentes, Iñaki
  • Rodríguez-Patón Aradas, Alfonso
Item Type: Presentation at Congress or Conference (Article)
Event Title: DNA Computing and Molecular ProgrammingLecture Notes in Computer Science Volume 7433, 2012
Event Dates: 14/08/2012 - 17/08/2012
Event Location: Aarhus, Dinamarca
Title of Book: DNA Computing and Molecular Programming
Date: 2012
ISBN: 978-3-642-32207-5
Volume: 7433
Subjects:
Faculty: Facultad de Informática (UPM)
Department: Inteligencia Artificial
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

We present a computing model based on the DNA strand displacement technique which performs Bayesian inference. The model will take single stranded DNA as input data, representing the presence or absence of a specific molecular signal (evidence). The program logic encodes the prior probability of a disease and the conditional probability of a signal given the disease playing with a set of different DNA complexes and their ratios. When the input and program molecules interact, they release a different pair of single stranded DNA species whose relative proportion represents the application of Bayes? Law: the conditional probability of the disease given the signal. The models presented in this paper can empower the application of probabilistic reasoning in genetic diagnosis in vitro.

More information

Item ID: 19355
DC Identifier: http://oa.upm.es/19355/
OAI Identifier: oai:oa.upm.es:19355
DOI: 10.1007/978-3-642-32208-2_9
Official URL: http://link.springer.com/chapter/10.1007%2F978-3-642-32208-2_9
Deposited by: Memoria Investigacion
Deposited on: 01 Oct 2013 17:27
Last Modified: 21 Apr 2016 17:37
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