Atlas-free Brain Tissue Segmentation Using a Single T1-weighted MRI Acquisition

Kober, Tobias; Roche, Alexis; Esteban Sanz-Dranguet, Oscar; Gorthi, Subrahmanyam; Rives, Delphine; Bach-Cuadra, Meritxell; Meuli, Reto y Krueger, Gunnar (2012). Atlas-free Brain Tissue Segmentation Using a Single T1-weighted MRI Acquisition. En: "20th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine", 05/05/2012 - 11/05/2012, Melbourne, Australia. p. 753.

Descripción

Título: Atlas-free Brain Tissue Segmentation Using a Single T1-weighted MRI Acquisition
Autor/es:
  • Kober, Tobias
  • Roche, Alexis
  • Esteban Sanz-Dranguet, Oscar
  • Gorthi, Subrahmanyam
  • Rives, Delphine
  • Bach-Cuadra, Meritxell
  • Meuli, Reto
  • Krueger, Gunnar
Tipo de Documento: Ponencia en Congreso o Jornada (Artículo)
Título del Evento: 20th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine
Fechas del Evento: 05/05/2012 - 11/05/2012
Lugar del Evento: Melbourne, Australia
Título del Libro: Proceedings of the international society for magnetic resonance in medicine
Fecha: Mayo 2012
Materias:
Escuela: E.T.S.I. Telecomunicación (UPM)
Departamento: Ingeniería Electrónica
Licencias Creative Commons: Reconocimiento - Sin obra derivada - No comercial

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Resumen

Many studies investigating the aging brain or disease-induced brain alterations rely on accurate and reproducible brain tissue segmentation. Being a preliminary processing step prior to the segmentation, reliableskull-stripping the removal ofnon-brain tissue is also crucial for all later image assessment. Typically, segmentation algorithms rely on an atlas i.e. pre-segmented template data. Brain morphology, however, differs considerably depending on age, sex and race. In addition, diseased brains may deviate significantly from the atlas information typically gained from healthy volunteers. The imposed prior atlas information can thus lead to degradation of segmentation results. The recently introduced MP2RAGE sequence provides a bias-free T1 contrast with heavily reduced T2*- and PD-weighting compared to the standard MP-RAGE [1]. To this end, it acquires two image volumes at different inversion times in one acquisition, combining them to a uniform, i.e. homogenous image. In this work, we exploit the advantageous contrast properties of the MP2RAGE and combine it with a Dixon (i.e. fat-water separation) approach. The information gained by the additional fat image of the head considerably improves the skull-stripping outcome [2]. In conjunction with the pure T1 contrast of the MP2RAGE uniform image, we achieve robust skull-stripping and brain tissue segmentation without the use of an atlas

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ID de Registro: 19796
Identificador DC: http://oa.upm.es/19796/
Identificador OAI: oai:oa.upm.es:19796
Depositado por: Memoria Investigacion
Depositado el: 21 Sep 2013 07:33
Ultima Modificación: 21 Abr 2016 21:16
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