Estimation of the effective number of founders that initiate an infection after aphid transmission of a multipartite plant virus

Betancourt Vásquez, Mónica and Fereres Castiel, Alberto and Fraile Pérez, Aurora and Garcia-Arenal Rodriguez, Fernando (2008). Estimation of the effective number of founders that initiate an infection after aphid transmission of a multipartite plant virus. "Journal of Virology", v. 82 (n. 24); pp. 12416-12421. ISSN 0022-538X. https://doi.org/10.1128/JVI.01542-08.

Description

Title: Estimation of the effective number of founders that initiate an infection after aphid transmission of a multipartite plant virus
Author/s:
  • Betancourt Vásquez, Mónica
  • Fereres Castiel, Alberto
  • Fraile Pérez, Aurora
  • Garcia-Arenal Rodriguez, Fernando
Item Type: Article
Título de Revista/Publicación: Journal of Virology
Date: December 2008
ISSN: 0022-538X
Volume: 82
Subjects:
Faculty: E.T.S.I. Agrónomos (UPM) [antigua denominación]
Department: Biotecnologia [hasta 2014]
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

The fecundity of RNA viruses can be very high. Thus, it is often assumed that viruses have large populations, and RNA virus evolution has been mostly explained using purely deterministic models. However, population bottlenecks during the virus life cycle could result in effective population numbers being much smaller than reported censuses, and random genetic drift could be important in virus evolution. A step at which population bottlenecks may be severe is host-to-host transmission. We report here an estimate of the size of the population that starts a new infection when Cucumber mosaic virus (CMV) is transmitted by the aphid Aphis gossypii, based on the segregation of two CMV genotypes in plants infected by aphids that acquired the virus from plants infected by both genotypes. Results show very small effective numbers of founders, between one and two, both in experiments in which the three-partite genome of CMV was aphid transmitted and in experiments in which a fourth RNA, CMV satellite RNA, was also transmitted. These numbers are very similar to those published for Potato virus Y, which has a monopartite genome and is transmitted by aphids according to a different mechanism than CMV. Thus, the number of genomic segments seems not to be a major determinant of the effective number of founders. Also, our results suggest that the occurrence of severe bottlenecks during horizontal transmission is general for viruses nonpersistently transmitted by aphids, indicating that random genetic drift should be considered when modeling virus evolution.

More information

Item ID: 2611
DC Identifier: http://oa.upm.es/2611/
OAI Identifier: oai:oa.upm.es:2611
DOI: 10.1128/JVI.01542-08
Official URL: http://jvi.asm.org/content/vol82/issue24/index.dtl
Deposited by: Memoria Investigacion
Deposited on: 18 Mar 2010 10:26
Last Modified: 20 Apr 2016 12:15
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