A new PET prototype for proton therapy: comparison of data and Monte Carlo simulations

Rosso, V.; Battistoni, Giuseppe; Belcari, Nicola; Camarlinghi, N.; Ferrari, A.; Ferretti, S.; Kraan, A.; Mairani, A.; Marino, N.; Ortuño Fisac, Juan Enrique; Pullia, M.; Sala Herraez, Jose Alberto; Santos Lleo, Andres de; Sportelli, Giancarlo; Straub, K. y Guerra, Alberto del (2013). A new PET prototype for proton therapy: comparison of data and Monte Carlo simulations. "Journal of Instrumentation", v. 8 ; pp. 1-6. ISSN 1748-0221. https://doi.org/10.1088/1748-0221/8/03/C03021.

Descripción

Título: A new PET prototype for proton therapy: comparison of data and Monte Carlo simulations
Autor/es:
  • Rosso, V.
  • Battistoni, Giuseppe
  • Belcari, Nicola
  • Camarlinghi, N.
  • Ferrari, A.
  • Ferretti, S.
  • Kraan, A.
  • Mairani, A.
  • Marino, N.
  • Ortuño Fisac, Juan Enrique
  • Pullia, M.
  • Sala Herraez, Jose Alberto
  • Santos Lleo, Andres de
  • Sportelli, Giancarlo
  • Straub, K.
  • Guerra, Alberto del
Tipo de Documento: Artículo
Título de Revista/Publicación: Journal of Instrumentation
Fecha: Marzo 2013
Volumen: 8
Materias:
Palabras Clave Informales: Instrumentation for hadron therapy, Gamma camera, SPECT, PET PET/CT, coronary CT angiography (CTA, Instrumentation for heavy-ion therapy
Escuela: E.T.S.I. Telecomunicación (UPM)
Departamento: Ingeniería Electrónica
Licencias Creative Commons: Reconocimiento - Sin obra derivada - No comercial

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Resumen

Ion beam therapy is a valuable method for the treatment of deep-seated and radio-resistant tumors thanks to the favorable depth-dose distribution characterized by the Bragg peak. Hadrontherapy facilities take advantage of the specific ion range, resulting in a highly conformal dose in the target volume, while the dose in critical organs is reduced as compared to photon therapy. The necessity to monitor the delivery precision, i.e. the ion range, is unquestionable, thus different approaches have been investigated, such as the detection of prompt photons or annihilation photons of positron emitter nuclei created during the therapeutic treatment. Based on the measurement of the induced β+ activity, our group has developed various in-beam PET prototypes: the one under test is composed by two planar detector heads, each one consisting of four modules with a total active area of 10 × 10 cm2. A single detector module is made of a LYSO crystal matrix coupled to a position sensitive photomultiplier and is read-out by dedicated frontend electronics. A preliminary data taking was performed at the Italian National Centre for Oncological Hadron Therapy (CNAO, Pavia), using proton beams in the energy range of 93–112 MeV impinging on a plastic phantom. The measured activity profiles are presented and compared with the simulated ones based on the Monte Carlo FLUKA package.

Más información

ID de Registro: 28897
Identificador DC: http://oa.upm.es/28897/
Identificador OAI: oai:oa.upm.es:28897
Identificador DOI: 10.1088/1748-0221/8/03/C03021
URL Oficial: http://iopscience.iop.org/1748-0221/8/03/C03021/
Depositado por: Memoria Investigacion
Depositado el: 04 Jun 2014 17:53
Ultima Modificación: 22 Sep 2014 11:43
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