A new PET prototype for proton therapy: comparison of data and Monte Carlo simulations

Rosso, V. and Battistoni, Giuseppe and Belcari, Nicola and Camarlinghi, N. and Ferrari, A. and Ferretti, S. and Kraan, A. and Mairani, A. and Marino, N. and Ortuño Fisac, Juan Enrique and Pullia, M. and Sala Herraez, Jose Alberto and Santos Lleo, Andres de and Sportelli, Giancarlo and Straub, K. and Guerra, Alberto del (2013). A new PET prototype for proton therapy: comparison of data and Monte Carlo simulations. "Journal of Instrumentation", v. 8 ; pp. 1-6. ISSN 1748-0221. https://doi.org/10.1088/1748-0221/8/03/C03021.

Description

Title: A new PET prototype for proton therapy: comparison of data and Monte Carlo simulations
Author/s:
  • Rosso, V.
  • Battistoni, Giuseppe
  • Belcari, Nicola
  • Camarlinghi, N.
  • Ferrari, A.
  • Ferretti, S.
  • Kraan, A.
  • Mairani, A.
  • Marino, N.
  • Ortuño Fisac, Juan Enrique
  • Pullia, M.
  • Sala Herraez, Jose Alberto
  • Santos Lleo, Andres de
  • Sportelli, Giancarlo
  • Straub, K.
  • Guerra, Alberto del
Item Type: Article
Título de Revista/Publicación: Journal of Instrumentation
Date: March 2013
ISSN: 1748-0221
Volume: 8
Subjects:
Freetext Keywords: Instrumentation for hadron therapy, Gamma camera, SPECT, PET PET/CT, coronary CT angiography (CTA, Instrumentation for heavy-ion therapy
Faculty: E.T.S.I. Telecomunicación (UPM)
Department: Ingeniería Electrónica
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

Ion beam therapy is a valuable method for the treatment of deep-seated and radio-resistant tumors thanks to the favorable depth-dose distribution characterized by the Bragg peak. Hadrontherapy facilities take advantage of the specific ion range, resulting in a highly conformal dose in the target volume, while the dose in critical organs is reduced as compared to photon therapy. The necessity to monitor the delivery precision, i.e. the ion range, is unquestionable, thus different approaches have been investigated, such as the detection of prompt photons or annihilation photons of positron emitter nuclei created during the therapeutic treatment. Based on the measurement of the induced β+ activity, our group has developed various in-beam PET prototypes: the one under test is composed by two planar detector heads, each one consisting of four modules with a total active area of 10 × 10 cm2. A single detector module is made of a LYSO crystal matrix coupled to a position sensitive photomultiplier and is read-out by dedicated frontend electronics. A preliminary data taking was performed at the Italian National Centre for Oncological Hadron Therapy (CNAO, Pavia), using proton beams in the energy range of 93–112 MeV impinging on a plastic phantom. The measured activity profiles are presented and compared with the simulated ones based on the Monte Carlo FLUKA package.

More information

Item ID: 28897
DC Identifier: http://oa.upm.es/28897/
OAI Identifier: oai:oa.upm.es:28897
DOI: 10.1088/1748-0221/8/03/C03021
Official URL: http://iopscience.iop.org/1748-0221/8/03/C03021/
Deposited by: Memoria Investigacion
Deposited on: 04 Jun 2014 17:53
Last Modified: 22 Sep 2014 11:43
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