QuantiDOPA: A Quantification Software for Dopaminergic Neurotransmission SPECT

Niñerola, A. and Martí Fuster, B. and Esteban, Oscar and Planes Cid, X. and Frangi Caregnato, A.F. and Ledesma Carbayo, María Jesús and Santos Lleo, Andres de and Cot, A. and Lomeña, F. and Pavía Segura, J. and Ros Puig, D. (2014). QuantiDOPA: A Quantification Software for Dopaminergic Neurotransmission SPECT. In: "XIII Mediterranean Conference on Medical and Biological Engineering and Computing 2013", 25/09/2013 - 28/09/2013, Seville, Spain. pp. 443-446. https://doi.org/10.1007/978-3-319-00846-2_110.

Description

Title: QuantiDOPA: A Quantification Software for Dopaminergic Neurotransmission SPECT
Author/s:
  • Niñerola, A.
  • Martí Fuster, B.
  • Esteban, Oscar
  • Planes Cid, X.
  • Frangi Caregnato, A.F.
  • Ledesma Carbayo, María Jesús
  • Santos Lleo, Andres de
  • Cot, A.
  • Lomeña, F.
  • Pavía Segura, J.
  • Ros Puig, D.
Item Type: Presentation at Congress or Conference (Article)
Event Title: XIII Mediterranean Conference on Medical and Biological Engineering and Computing 2013
Event Dates: 25/09/2013 - 28/09/2013
Event Location: Seville, Spain
Title of Book: IFMBE Proceedings
Date: 2014
Volume: 41
Subjects:
Freetext Keywords: Quantificatio,n dopaminergic system, Parkinson’s disease, SPECT GIMIAS
Faculty: E.T.S.I. Telecomunicación (UPM)
Department: Ingeniería Electrónica
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

Quantification of neurotransmission Single-Photon Emission Computed Tomography (SPECT) studies of the dopaminergic system can be used to track, stage and facilitate early diagnosis of the disease. The aim of this study was to implement QuantiDOPA, a semi-automatic quantification software of application in clinical routine to reconstruct and quantify neurotransmission SPECT studies using radioligands which bind the dopamine transporter (DAT). To this end, a workflow oriented framework for the biomedical imaging (GIMIAS) was employed. QuantiDOPA allows the user to perform a semiautomatic quantification of striatal uptake by following three stages: reconstruction, normalization and quantification. QuantiDOPA is a useful tool for semi-automatic quantification inDAT SPECT imaging and it has revealed simple and flexible

More information

Item ID: 29922
DC Identifier: http://oa.upm.es/29922/
OAI Identifier: oai:oa.upm.es:29922
DOI: 10.1007/978-3-319-00846-2_110
Official URL: http://link.springer.com/chapter/10.1007%2F978-3-319-00846-2_110
Deposited by: Memoria Investigacion
Deposited on: 09 Aug 2014 11:36
Last Modified: 02 Oct 2014 22:56
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