Niñerola, A. and Martí Fuster, B. and Esteban, Oscar and Planes Cid, X. and Frangi Caregnato, A.F. and Ledesma Carbayo, María Jesús and Santos Lleo, Andres de and Cot, A. and Lomeña, F. and Pavía Segura, J. and Ros Puig, D.
QuantiDOPA: A Quantification Software for Dopaminergic Neurotransmission SPECT.
In: "XIII Mediterranean Conference on Medical and Biological Engineering and Computing 2013", 25/09/2013 - 28/09/2013, Seville, Spain. pp. 443-446.
Quantification of neurotransmission Single-Photon Emission Computed Tomography (SPECT) studies of the dopaminergic system can be used to track, stage and facilitate early diagnosis of the disease. The aim of this study was to implement QuantiDOPA, a semi-automatic quantification software of application in clinical routine to reconstruct and quantify neurotransmission SPECT studies using radioligands which bind the dopamine transporter (DAT). To this end, a workflow oriented framework for the biomedical imaging (GIMIAS) was employed. QuantiDOPA allows the user to perform a semiautomatic quantification of striatal uptake by following three stages: reconstruction, normalization and quantification. QuantiDOPA is a useful tool for semi-automatic quantification inDAT SPECT imaging and it has revealed simple and flexible