A method to obtain the thermal parameters and the photothermal transduction efficiency in an optical hyperthermia device based on laser irradiation of gold nanoparticles

Sánchez López de Pablo, Cristina and Serrano Olmedo, Jose Javier and Mina Rosales, Alejandra and Ramírez Hernández, Norma and Pozo Guerrero, Francisco del (2014). A method to obtain the thermal parameters and the photothermal transduction efficiency in an optical hyperthermia device based on laser irradiation of gold nanoparticles. "Nanoscale Research Letters", v. 9 (n. 441); pp. 1-7. ISSN 1931-7573. https://doi.org/10.1186/1556-276X-9-441.

Description

Title: A method to obtain the thermal parameters and the photothermal transduction efficiency in an optical hyperthermia device based on laser irradiation of gold nanoparticles
Author/s:
  • Sánchez López de Pablo, Cristina
  • Serrano Olmedo, Jose Javier
  • Mina Rosales, Alejandra
  • Ramírez Hernández, Norma
  • Pozo Guerrero, Francisco del
Item Type: Article
Título de Revista/Publicación: Nanoscale Research Letters
Date: August 2014
ISSN: 1931-7573
Volume: 9
Subjects:
Freetext Keywords: Gold nanoparticles; Laser irradiation; Optical hyperthermia; Photothermal transduction efficiency; Temperature curves; Thermal parameters
Faculty: Centro de Tecnología Biomédica (CTB) (UPM)
Department: Otro
Creative Commons Licenses: Recognition - No derivative works - Non commercial

Full text

[img]
Preview
PDF - Requires a PDF viewer, such as GSview, Xpdf or Adobe Acrobat Reader
Download (3MB) | Preview

Abstract

Optical hyperthermia systems based on the laser irradiation of gold nanorods seem to be a promising tool in the development of therapies against cancer. After a proof of concept in which the authors demonstrated the efficiency of this kind of systems, a modeling process based on an equivalent thermal-electric circuit has been carried out to determine the thermal parameters of the system and an energy balance obtained from the time-dependent heating and cooling temperature curves of the irradiated samples in order to obtain the photothermal transduction efficiency. By knowing this parameter, it is possible to increase the effectiveness of the treatments, thanks to the possibility of predicting the response of the device depending on the working configuration. As an example, the thermal behavior of two different kinds of nanoparticles is compared. The results show that, under identical conditions, the use of PEGylated gold nanorods allows for a more efficient heating compared with bare nanorods, and therefore, it results in a more effective therapy.

More information

Item ID: 30832
DC Identifier: http://oa.upm.es/30832/
OAI Identifier: oai:oa.upm.es:30832
DOI: 10.1186/1556-276X-9-441
Official URL: http://www.nanoscalereslett.com/content/pdf/1556-276X-9-441.pdf
Deposited by: Memoria Investigacion
Deposited on: 11 Apr 2015 11:22
Last Modified: 11 Apr 2015 11:22
  • Logo InvestigaM (UPM)
  • Logo GEOUP4
  • Logo Open Access
  • Open Access
  • Logo Sherpa/Romeo
    Check whether the anglo-saxon journal in which you have published an article allows you to also publish it under open access.
  • Logo Dulcinea
    Check whether the spanish journal in which you have published an article allows you to also publish it under open access.
  • Logo de Recolecta
  • Logo del Observatorio I+D+i UPM
  • Logo de OpenCourseWare UPM