Atlantic Salmon (Salmo salar L.) as a Marine Functional Source of Gamma-Tocopherol

Menoyo Luque, David and Sanz Bayón, Carmen and Nessa, Anna Hesby and Esatbeyoglu, Tuba and Faizan, Mohammad and Pallauf, Kathrin and Diego, Nuria de and Wagner, Anika Eva and Ipharraguerre, Ignacio and Stubhaug, Ingunn and Rimbach, Gerald (2014). Atlantic Salmon (Salmo salar L.) as a Marine Functional Source of Gamma-Tocopherol. "Marine Drugs", v. 12 (n. 12); pp. 5944-5959. ISSN 1660-3397. https://doi.org/10.3390/md12125944.

Description

Title: Atlantic Salmon (Salmo salar L.) as a Marine Functional Source of Gamma-Tocopherol
Author/s:
  • Menoyo Luque, David
  • Sanz Bayón, Carmen
  • Nessa, Anna Hesby
  • Esatbeyoglu, Tuba
  • Faizan, Mohammad
  • Pallauf, Kathrin
  • Diego, Nuria de
  • Wagner, Anika Eva
  • Ipharraguerre, Ignacio
  • Stubhaug, Ingunn
  • Rimbach, Gerald
Item Type: Article
Título de Revista/Publicación: Marine Drugs
Date: December 2014
ISSN: 1660-3397
Volume: 12
Subjects:
Faculty: E.T.S.I. Agrónomos (UPM) [antigua denominación]
Department: Producción Agraria
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

Gamma tocopherol (gT) exhibits beneficial cardiovascular effects partly due to its anti-inflammatory activity. Important sources of gT are vegetable oils. However, little is known to what extent gT can be transferred into marine animal species such as Atlantic salmon by feeding. Therefore, in this study we have investigated the transfer of dietary gT into salmon. To this end, fish were fed a diet supplemented with 170 ppm gT for 16 weeks whereby alpha tocopherol levels were adjusted to 190 ppm in this and the control diet. Feeding gT-rich diets resulted in a three-fold increase in gT concentrations in the liver and fillet compared to non-gT-supplemented controls. Tissue alpha tocopherol levels were not decreased indicating no antagonistic interaction between gamma- and alpha tocopherol in salmon. The concentration of total omega 3 fatty acids slightly increased in response to dietary gT. Furthermore, dietary gT significantly decreased malondialdehyde in the fillet, determined as a biomarker of lipid peroxidation. In the liver of gT fed salmon we observed an overall down-regulation of genes involved in lipid homeostasis. Additionally, gT improved the antioxidant capacity by up-regulating Gpx4a gene expression in the pyloric caeca. We suggest that Atlantic salmon may provide a marine functional source capable of enriching gT for human consumption.

Funding Projects

TypeCodeAcronymLeaderTitle
FP7285856OMEGA3MAXUNIVERSIDAD POLITECNICA DE MADRIDMaximizing marine omega-3 retention in farmed fish: sustainable production of healthy food

More information

Item ID: 35496
DC Identifier: http://oa.upm.es/35496/
OAI Identifier: oai:oa.upm.es:35496
DOI: 10.3390/md12125944
Official URL: http://www.mdpi.com/1660-3397/12/12/5944
Deposited by: Memoria Investigacion
Deposited on: 01 Jun 2015 13:53
Last Modified: 16 May 2019 10:47
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