Rapid prototyping of multi-scale biomedical microdevices by combining additive manufacturing technologies

Hengsbach, Stefan and Diaz Lantada, Andres (2014). Rapid prototyping of multi-scale biomedical microdevices by combining additive manufacturing technologies. "Biomedical Microdevices", v. 16 (n. 4); pp. 617-627. ISSN 1387-2176. https://doi.org/10.1007/s10544-014-9864-2.

Description

Title: Rapid prototyping of multi-scale biomedical microdevices by combining additive manufacturing technologies
Author/s:
  • Hengsbach, Stefan
  • Diaz Lantada, Andres
Item Type: Article
Título de Revista/Publicación: Biomedical Microdevices
Date: August 2014
ISSN: 1387-2176
Volume: 16
Subjects:
Freetext Keywords: Fractals; Surface topography; Material texture; Materials design; Computer-aided design; Additive manufacturing; Direct laser writing
Faculty: E.T.S.I. Industriales (UPM)
Department: Ingeniería Mecánica
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

The possibility of designing and manufacturing biomedical microdevices with multiple length-scale geometries can help to promote special interactions both with their environment and with surrounding biological systems. These interactions aim to enhance biocompatibility and overall performance by using biomimetic approaches. In this paper, we present a design and manufacturing procedure for obtaining multi-scale biomedical microsystems based on the combination of two additive manufacturing processes: a conventional laser writer to manufacture the overall device structure, and a direct-laser writer based on two-photon polymerization to yield finer details. The process excels for its versatility, accuracy and manufacturing speed and allows for the manufacture of microsystems and implants with overall sizes up to several millimeters and with details down to sub-micrometric structures. As an application example we have focused on manufacturing a biomedical microsystem to analyze the impact of microtextured surfaces on cell motility. This process yielded a relevant increase in precision and manufacturing speed when compared with more conventional rapid prototyping procedures.

Funding Projects

TypeCodeAcronymLeaderTitle
FP7226460EUMINAfabKarlsruher Institut fur TechnologieIntegrating European research infrastructures for micro-nano fabrication of functional structures and devices out of a knowledge-based multimaterials repertoire

More information

Item ID: 35847
DC Identifier: http://oa.upm.es/35847/
OAI Identifier: oai:oa.upm.es:35847
DOI: 10.1007/s10544-014-9864-2
Official URL: http://link.springer.com/article/10.1007/s10544-014-9864-2
Deposited by: Memoria Investigacion
Deposited on: 11 Mar 2016 09:10
Last Modified: 11 Mar 2016 09:10
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