Hyperconnectivity is a fundamental response to neurological disruption

Hillary, Frank G. and Román, Cristina A. and Venkatesan, Umesh and Rajtmajer, Sarah and Bajo Breton, Ricardo and Castellanos, Nazareth (2015). Hyperconnectivity is a fundamental response to neurological disruption. "Neuropsychology", v. 1 (n. 29); pp. 59-75. ISSN 0894-4105. https://doi.org/10.1037/neu0000110.

Description

Title: Hyperconnectivity is a fundamental response to neurological disruption
Author/s:
  • Hillary, Frank G.
  • Román, Cristina A.
  • Venkatesan, Umesh
  • Rajtmajer, Sarah
  • Bajo Breton, Ricardo
  • Castellanos, Nazareth
Item Type: Article
Título de Revista/Publicación: Neuropsychology
Date: January 2015
ISSN: 0894-4105
Volume: 1
Subjects:
Freetext Keywords: brain injury, Multiple Sclerosis, Alzheimer’s Disease, connectivity, default mode network
Faculty: Centro de Tecnología Biomédica (CTB) (UPM)
Department: Tecnología Fotónica y Bioingeniería
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

In the cognitive and clinical neurosciences, the past decade has been marked by dramatic growth in a literature examining brain "connectivity" using noninvasive methods. We offer a critical review of the blood oxygen level dependent functional MRI (BOLD fMRI) literature examining neural connectivity changes in neurological disorders with focus on brain injury and dementia. The goal is to demonstrate that there are identifiable shifts in local and large-scale network connectivity that can be predicted by the degree of pathology. We anticipate that the most common network response to neurological insult is hyperconnectivity but that this response depends upon demand and resource availability.

More information

Item ID: 41078
DC Identifier: http://oa.upm.es/41078/
OAI Identifier: oai:oa.upm.es:41078
DOI: 10.1037/neu0000110
Official URL: https://psycnet.apa.org/record/2014-24829-001?doi=1
Deposited by: Memoria Investigacion
Deposited on: 07 May 2017 08:59
Last Modified: 06 Jun 2019 14:11
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