Phase space determination from measured dose data for intraoperative electron radiation therapy

Herranz, E. and Herraiz, J.L. and Ibáñez, P. and Pérez Liva, Mailyn and Puebla, R. and Cal González, Jacobo and Guerra, P. and Rodríguez, R. and Illana Alejandro, Carlos and Udías Moinelo, José Manuel (2014). Phase space determination from measured dose data for intraoperative electron radiation therapy. "Physics in Medicine and Biology", v. 60 ; pp. 375-401. ISSN 0031-9155. https://doi.org/10.1088/0031-9155/60/1/375.

Description

Title: Phase space determination from measured dose data for intraoperative electron radiation therapy
Author/s:
  • Herranz, E.
  • Herraiz, J.L.
  • Ibáñez, P.
  • Pérez Liva, Mailyn
  • Puebla, R.
  • Cal González, Jacobo
  • Guerra, P.
  • Rodríguez, R.
  • Illana Alejandro, Carlos
  • Udías Moinelo, José Manuel
Item Type: Article
Título de Revista/Publicación: Physics in Medicine and Biology
Date: December 2014
ISSN: 0031-9155
Volume: 60
Subjects:
Freetext Keywords: Monte Carlo simulations, intraoperative radiotherapy, phase space
Faculty: E.T.S.I. Telecomunicación (UPM)
Department: Ingeniería Electrónica
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

A procedure to characterize beams of a medical linear accelerator for their use in Monte Carlo (MC) dose calculations for intraoperative electron radiation therapy (IOERT) is presented. The procedure relies on dose measurements in homogeneous media as input, avoiding the need for detailed simulations of the accelerator head. An iterative algorithm (EM-ML) has been employed to extract the relevant details of the phase space (PHSP) of the particles coming from the accelerator, such as energy spectra, spatial distribution and angle of emission of particles. The algorithm can use pre-computed dose volumes in water and/or air, so that the machine-specific tuning with actual data can be performed in a few minutes. To test the procedure, MC simulations of a linear accelerator with typical IOERT applicators and energies, have been performed and taken as reference. A solution PHSP derived from the dose produced by the simulated accelerator has been compared to the reference PHSP. Further, dose delivered by the simulated accelerator for setups not included in the fit of the PHSP were compared to the ones derived from the solution PHSP. The results show that it is possible to derive from dose measurements PHSP accurate for IOERT MC dose estimations.

Funding Projects

TypeCodeAcronymLeaderTitle
Madrid Regional GovernmentARTEMIS S2009/DPI-1802UnspecifiedUnspecifiedUnspecified
Government of SpainTEC2010-21619-C04UnspecifiedMinisterio de Ciencia e InnovaciónUnspecified
Government of SpainFPA2010-17142UnspecifiedMinisterio de Ciencia e InnovaciónUnspecified
Government of SpainPSE-300000-2009-5ENTEPRASEMinisterio de Ciencia e InnovaciónUnspecified
Government of SpainIPT-300000-2010-3PRECISIONMinisterio de Ciencia e InnovaciónUnspecified
Government of SpainIPT- 2012-0401-300000UnspecifiedMinisterio de Ciencia e InnovaciónUnspecified

More information

Item ID: 41101
DC Identifier: http://oa.upm.es/41101/
OAI Identifier: oai:oa.upm.es:41101
DOI: 10.1088/0031-9155/60/1/375
Official URL: http://iopscience.iop.org/article/10.1088/0031-9155/60/1/375/meta;jsessionid=DAD32364B6B790A816F90CFAC7E4F26B.c3.iopscience.cld.iop.org
Deposited by: Memoria Investigacion
Deposited on: 03 Jul 2016 08:27
Last Modified: 03 Jul 2016 08:27
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