Sensitive detection of major food allergens in breast milk: first gateway for allergenic contact during breastfeeding

Pastor Vargas, Carlos and Maroto, A. S. and Diaz Perales, Araceli and Villalba, M. and Casillas Díaz, N. and Vivanco, Fernando and Cuesta Herranz, J. (2015). Sensitive detection of major food allergens in breast milk: first gateway for allergenic contact during breastfeeding. "Allergy", v. 70 (n. 8); pp. 1024-1027. ISSN 0105-4538. https://doi.org/10.1111/all.12646.

Description

Title: Sensitive detection of major food allergens in breast milk: first gateway for allergenic contact during breastfeeding
Author/s:
  • Pastor Vargas, Carlos
  • Maroto, A. S.
  • Diaz Perales, Araceli
  • Villalba, M.
  • Casillas Díaz, N.
  • Vivanco, Fernando
  • Cuesta Herranz, J.
Item Type: Article
Título de Revista/Publicación: Allergy
Date: August 2015
Volume: 70
Subjects:
Faculty: E.T.S.I. Agrónomos (UPM) [antigua denominación]
Department: Biotecnología - Biología Vegetal
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

Food allergy is recognized as a major public health issue, especially in early childhood. It has been hypothesized that early sensitization to food allergens maybe due to their ingestion as components dissolved in the milk during the breastfeeding, explaining reaction to a food, which has never been taken before. Thus, the aim of this work has been to detect the presence of the food allergens in breast milk by microarray technology. We produced a homemade microarray with antibodies produced against major food allergens. The antibody microarray was incubated with breast milk from 14 women collected from Fundación Jiménez Díaz Hospital. In this way, we demonstrated the presence of major foods allergens in breast milk. The analysis of allergens presented in breast milk could be a useful tool in allergy prevention and could provide us a key data on the role of this feeding in tolerance induction or sensitization in children.

More information

Item ID: 41272
DC Identifier: http://oa.upm.es/41272/
OAI Identifier: oai:oa.upm.es:41272
DOI: 10.1111/all.12646
Official URL: http://onlinelibrary.wiley.com/doi/10.1111/all.12646/abstract
Deposited by: Memoria Investigacion
Deposited on: 21 Jun 2016 17:07
Last Modified: 31 Aug 2016 22:30
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