Impact of physical activity and cardiovascular fitness on total homocysteine concentrations in European adolescents : The HELENA Study

Benser, Jasmín and Valtueña Santamaría, Jara and Ruíz, Jonathan R. and Mielgo Ayuso, Juan Francisco and Breidenassel, Christina and Vicente Rodríguez, Germán and Ferrari, Marika and Widhalm, Kurt and Manios, Yannis and Sjöstrom, Michael and Molnar,, Dénes and Gomez Martínez, Sonia and Kafatos, Antony and Palacios Le Blé, Gonzalo and Moreno, Luís A. and Castillo, Manuel J. and Stehle, Peter and González Gross, Marcela (2015). Impact of physical activity and cardiovascular fitness on total homocysteine concentrations in European adolescents : The HELENA Study. "Journal of Nutritional Science and Vitaminology", v. 61 (n. 1); pp. 45-54. ISSN 0301-4800. https://doi.org/10.3177/jnsv.61.45.

Description

Title: Impact of physical activity and cardiovascular fitness on total homocysteine concentrations in European adolescents : The HELENA Study
Author/s:
  • Benser, Jasmín
  • Valtueña Santamaría, Jara
  • Ruíz, Jonathan R.
  • Mielgo Ayuso, Juan Francisco
  • Breidenassel, Christina
  • Vicente Rodríguez, Germán
  • Ferrari, Marika
  • Widhalm, Kurt
  • Manios, Yannis
  • Sjöstrom, Michael
  • Molnar,, Dénes
  • Gomez Martínez, Sonia
  • Kafatos, Antony
  • Palacios Le Blé, Gonzalo
  • Moreno, Luís A.
  • Castillo, Manuel J.
  • Stehle, Peter
  • González Gross, Marcela
Item Type: Article
Título de Revista/Publicación: Journal of Nutritional Science and Vitaminology
Date: 2015
ISSN: 0301-4800
Volume: 61
Subjects:
Freetext Keywords: homocysteine; physical activity; cardiovascular fitness; body constitution
Faculty: Facultad de Ciencias de la Actividad Física y del Deporte (INEF) (UPM)
Department: Salud y Rendimiento Humano
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

We examined the association of physical activity (PA), cardiovascular fi tness (CVF) and fatness with total homocysteine (tHcy) concentrations in European adolescents. The present study comprised 713 European adolescents aged 14.81.2 y (females 55.3%) from the multicenter HELENA cross-sectional study. PA was assessed through accelerometry, CVF by the 20-m shuttle run test, and body fat by skinfold thicknesses with the Slaughter equation. Plasma folate, cobalamin, and tHcy concentrations were measured. To examine the association of tHcy with PA, CVF, and fatness after controlling for a set of confounders including age, maturity, folate, cobalamin, creatinine, smoking, supplement use, and methylenetetrahydrofolate reductase 677 genotype (CC 47%, CT 43%, TT 10%), bivariate correlations followed by multiple regression models were performed. In the bivariate correlation analysis, tHcy concentrations were slightly negatively correlated (p0.05) with CVF in females (measured both by stages: r 0.118 and by VO2max: r 0.102) and positively with body mass index (r 0.100). However, daily time spent with moderate and vigorous PA showed a weak positive association with tHcy in females (p0.05). tHcy concentrations showed a tendency to decrease with increasing CVF and increase with increasing BMI in female European adolescents. However, tHcy concentrations were positively associated with moderate and vigorous PA in female European adolescents.

More information

Item ID: 41422
DC Identifier: http://oa.upm.es/41422/
OAI Identifier: oai:oa.upm.es:41422
DOI: 10.3177/jnsv.61.45
Official URL: https://www.jstage.jst.go.jp/article/jnsv/61/1/61_45/_article
Deposited by: Memoria Investigacion
Deposited on: 16 Sep 2016 09:33
Last Modified: 07 Jun 2019 15:22
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