Laminar differences in dendritic structure of pyramidal neurons in the juvenile rat somatosensory cortex

Rojo, Concepción and Leguey Vitoriano, Ignacio and Kastanauskaite, Asta and Bielza Lozoya, María Concepción and Larrañaga Múgica, Pedro María and Felipe Oroquieta, Javier de and Benavides Piccione, Ruth (2016). Laminar differences in dendritic structure of pyramidal neurons in the juvenile rat somatosensory cortex. "Cerebral Cortex", v. 26 (n. 6); pp. 2811-2822. ISSN 1047-3211. https://doi.org/10.1093/cercor/bhv316.

Description

Title: Laminar differences in dendritic structure of pyramidal neurons in the juvenile rat somatosensory cortex
Author/s:
  • Rojo, Concepción
  • Leguey Vitoriano, Ignacio
  • Kastanauskaite, Asta
  • Bielza Lozoya, María Concepción
  • Larrañaga Múgica, Pedro María
  • Felipe Oroquieta, Javier de
  • Benavides Piccione, Ruth
Item Type: Article
Título de Revista/Publicación: Cerebral Cortex
Date: 2016
ISSN: 1047-3211
Volume: 26
Subjects:
Freetext Keywords: 3D reconstructions; Branching pattern; Cerebral cortex; Cortical layer; Intracellular injections; Lucifer yellow; Statistical univariate analysis
Faculty: E.T.S. de Ingenieros Informáticos (UPM)
Department: Inteligencia Artificial
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

Pyramidal cell structure varies between different cortical areas and species, indicating that the cortical circuits that these cells participate in are likely to be characterized by different functional capabilities. Structural differences between cortical layers have been traditionally reported using either the Golgi method or intracellular labeling, but the structure of pyramidal cells has not previously been systematically analyzed across all cortical layers at a particular age. In the present study, we investigated the dendritic architecture of complete basal arbors of pyramidal neurons in layers II, III, IV, Va, Vb, and VI of the hindlimb somatosensory cortical region of postnatal day 14 rats. We found that the characteristics of basal dendritic morphologies are statistically different in each cortical layer. The variations in size and branching pattern that exist between pyramidal cells of different cortical layers probably re flect the particular functional propertiesthat are characteristic of the cortical circuit in which they participate. This new set of complete basal dendritic arbors of 3D-reconstructed pyramidal cell morphologies across each cortical layer will provide new insights into interlaminar information processing in the cerebral cortex.

Funding Projects

TypeCodeAcronymLeaderTitle
Government of SpainC080020-09UnspecifiedUnspecifiedCajal Blue Brain
Government of SpainTIN2013-41592-PUnspecifiedUnspecifiedAprendizaje de redes bayesianas con variables sin y con direccionalidad para descubrimiento de asociaciones, predicción multirespuesta y clustering
FP7604102HBPUnspecifiedThe Human Brain Project
Madrid Regional GovernmentS2013/ICE-2845CASI – CAMUnspecifiedConceptos y aplicaciones de los sistemas inteligentes

More information

Item ID: 46292
DC Identifier: http://oa.upm.es/46292/
OAI Identifier: oai:oa.upm.es:46292
DOI: 10.1093/cercor/bhv316
Official URL: https://academic.oup.com/cercor/article/26/6/2811/1754287
Deposited by: Memoria Investigacion
Deposited on: 30 Jan 2018 10:38
Last Modified: 22 Mar 2019 15:29
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