Functional and structural brain connectivity of young binge drinkers: a follow-up study

Correas Marín, Ángeles and Cuesta Prieto, Pablo and López Caneda, E. and Rodríguez Holguin, S. and García Moreno, L. M. and Pineda Pardo, José Ángel and Cadaveira, F. and Maestu Unturbe, Fernando (2016). Functional and structural brain connectivity of young binge drinkers: a follow-up study. "Bioscience Reports", v. 6 ; pp. 31293-1. ISSN 0144-8463. https://doi.org/10.1038/srep31293.

Description

Title: Functional and structural brain connectivity of young binge drinkers: a follow-up study
Author/s:
  • Correas Marín, Ángeles
  • Cuesta Prieto, Pablo
  • López Caneda, E.
  • Rodríguez Holguin, S.
  • García Moreno, L. M.
  • Pineda Pardo, José Ángel
  • Cadaveira, F.
  • Maestu Unturbe, Fernando
Item Type: Article
Título de Revista/Publicación: Bioscience Reports
Date: August 2016
ISSN: 0144-8463
Volume: 6
Subjects:
Faculty: Centro de Tecnología Biomédica (CTB) (UPM)
Department: Otro
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

Adolescence is a period of ongoing brain maturation characterized by hierarchical changes in the functional and structural networks. For this reason, the young brain is particularly vulnerable to the toxic effects of alcohol. Nowadays, binge drinking is a pattern of alcohol consumption increasingly prevalent among adolescents. The aim of the present study is to evaluate the evolution of the functional and anatomical connectivity of the Default Mode Network (DMN) in young binge drinkers along two years. Magnetoencephalography signal during eyes closed resting state as well as Diffusion Tensor Imaging (DTI) were acquired twice within a 2-year interval from 39 undergraduate students (22 controls, 17 binge drinkers) with neither personal nor family history of alcoholism. The group comparison showed that, after maintaining a binge drinking pattern along at least two years, binge drinkers displayed an increased brain connectivity of the DMN in comparison with the control group. On the other hand, the structural connectivity did not show significant differences neither between groups nor over the time. These findings point out that a continued pattern of binge drinking leads to functional alterations in the normal brain maturation process, even before anatomical changes can be detected.

Funding Projects

TypeCodeAcronymLeaderTitle
Government of SpainSPI/2010/051UnspecifiedUnspecifiedUnspecified

More information

Item ID: 47985
DC Identifier: http://oa.upm.es/47985/
OAI Identifier: oai:oa.upm.es:47985
DOI: 10.1038/srep31293
Official URL: http://www.usc.es/necea/publicacion/c5e8df894d3b/?lang=en
Deposited by: Memoria Investigacion
Deposited on: 12 Dec 2018 08:35
Last Modified: 12 Dec 2018 08:35
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