Texto completo
|
PDF (Document Portable Format)
- Se necesita un visor de ficheros PDF, como GSview, Xpdf o Adobe Acrobat Reader
Descargar (1MB) | Vista Previa |
Antigen-Antibody Affinity for Dry Eye Biomarkers by Label Free Biosensing. Comparison with the ELISA Technique
Cita
Laguna Heras, Maria Fe; Holgado Bolaños, Miguel; López Hernández, Ana; Santamaría Fernández, Beatriz; Lavín Hueros, Álvaro; Soria, Javier; Suarez, Tatiana; Bardina, Carlota; Jara, Mónica; Sanza Gutiérrez, Francisco Javier y Casquel Del Campo, Rafael (2015). Antigen-Antibody Affinity for Dry Eye Biomarkers by Label Free Biosensing. Comparison with the ELISA Technique. "Sensors", v. 15 ; pp. 19819-19829. ISSN 1424-8220. https://doi.org/10.3390/s150819819.
Descripción
| Título: | Antigen-Antibody Affinity for Dry Eye Biomarkers by Label Free Biosensing. Comparison with the ELISA Technique |
|---|---|
| Autor/es: |
|
| Tipo de Documento: | Artículo |
| Título de Revista/Publicación: | Sensors |
| Fecha: | 2015 |
| Volumen: | 15 |
| Materias: | |
| Palabras Clave Informales: | photonic sensing cells BICELLs; biosensors; label-free immunoassay; dry eye biomarkers |
| Escuela: | E.T.S.I. Industriales (UPM) |
| Departamento: | Física Aplicada e Ingeniería de Materiales |
| Licencias Creative Commons: | Reconocimiento - Sin obra derivada - No comercial |
Resumen
The specificity and affinity of antibody-antigen interactions is a fundamental way to achieve reliable biosensing responses. Different proteins involved with dry eye dysfunction: ANXA1, ANXA11, CST4, PRDX5, PLAA and S100A6; were validated as biomarkers. In this work several antibodies were tested for ANXA1, ANXA11 and PRDX5 to select the best candidates for each biomarker. The results were obtained by using Biophotonic Sensing Cells (BICELLs) as an efficient methodology for label-free biosensing and compared with the Enzyme-Linked Immuno Sorbent Assay (ELISA) technique.
Proyectos asociados
| Tipo | Código | Acrónimo | Responsable | Título |
|---|---|---|---|---|
| Gobierno de España | IPT-2011-1429-010000 | INNBIOD | Sin especificar | INNovación y desarrollo de sistemas portátiles de detección BIOlógica Óptica de alta eficiencia |
| Gobierno de España | TEC2012-31145 | Sin especificar | Sin especificar | Project PLATON |
| FP7 | 614057 | ENVIGUARD | Sin especificar | Development of a biosensor technology for environmental monitoring and disease prevention in aquaculture ensuring food safety |
Más información
| ID de Registro: | 50265 |
|---|---|
| Identificador DC: | http://oa.upm.es/50265/ |
| Identificador OAI: | oai:oa.upm.es:50265 |
| Identificador DOI: | 10.3390/s150819819 |
| URL Oficial: | http://www.mdpi.com/1424-8220/15/8/19819 |
| Depositado por: | Memoria Investigacion |
| Depositado el: | 04 Jun 2018 14:56 |
| Ultima Modificación: | 04 Jun 2018 14:56 |
