Linear closed-loop control using Luenberger observer applied to insulin administration for type 1 diabetes

Orozco López, Onofré and Castañeda, Carlos E. and Rodríguez Herrero, Agustín and García Sáez, Gema and Hernando Pérez, María Elena (2017). Linear closed-loop control using Luenberger observer applied to insulin administration for type 1 diabetes. In: "Fifth International Conference on Advances in Mechanical and Robotics Engineering - AMRE 2017", 27/05/2017 - 28/05/2017, Roma (Italia). ISBN 78-1-63248-123-8. pp. 27-32. https://doi.org/10.15224/978-1-63248-123-8-19.

Description

Title: Linear closed-loop control using Luenberger observer applied to insulin administration for type 1 diabetes
Author/s:
  • Orozco López, Onofré
  • Castañeda, Carlos E.
  • Rodríguez Herrero, Agustín
  • García Sáez, Gema
  • Hernando Pérez, María Elena
Item Type: Presentation at Congress or Conference (Article)
Event Title: Fifth International Conference on Advances in Mechanical and Robotics Engineering - AMRE 2017
Event Dates: 27/05/2017 - 28/05/2017
Event Location: Roma (Italia)
Title of Book: Proceedings of the Fifth International Conference on Advances in Mechanical and Robotics Engineering - AMRE 2017
Date: 2017
ISBN: 78-1-63248-123-8
Subjects:
Freetext Keywords: Luenberger observer, Bergman model, artificial pancreas, type 1 diabetes
Faculty: E.T.S.I. y Sistemas de Telecomunicación (UPM)
Department: Ingeniería Telemática y Electrónica
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

In this work the design of a Luenberger observer is proposed to estimate the unmeasurable state space variables from Hovorka?s model. This model is linearized and evaluated in an operation point where Luenberger observer is designed using the Ackermann methodology. The observer is employed to estimate the unmeasurable variables of virtual patients which are generated by Bergman?s model. Once the unmeasurable state variables are obtained by the Luenberger observer using only the input-output information of the Bergman?s model, a control algorithm based on eigenvalues relocation trough Ackermann methodology for linear systems is applied. In this methodology, a constant feedback gain vector is obtained in order to compute the control signal (insulin) to be applied to virtual patient and keep on normoglycemia rank. The carbohydrates ingestion is considered as the main disturbances. In order to assess the proposed methodology, two tests are designed: the first one consists of changing the reference signal in order to evaluate the control sensitivity; and the second one includes different proportions of prandial insulin used in open-loop to try the controller response under distinct operation conditions. The results are obtained via simulation using Simulink of Matlab.

More information

Item ID: 50756
DC Identifier: http://oa.upm.es/50756/
OAI Identifier: oai:oa.upm.es:50756
DOI: 10.15224/978-1-63248-123-8-19
Deposited by: Memoria Investigacion
Deposited on: 30 May 2018 10:19
Last Modified: 31 May 2018 05:44
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