REGIA, an EU project on functional genomics of transcription factors from Arabidopsis thaliana

Paz Ares, Javier and Valencia, Alfonso and Costantino, Paolo and Vittorioso, Paola and Davies, Brendan and Gilmartin, Phil and Giraudat, Jerome and Parcy, François and Reindl, Andreas and Sablowski, Robert and Coupland, George and Martin, Cathie and Angenent, Cerco C. and Baumlein, Helmut and Mock, Hans Peter and Carbonero Zalduegui, Pilar and Colombo, Lucia and Tonelli, Chiara and Engström, Peter and Dröege-Laser, Wolfgang and Gatz, Christiane and Kavanagh, Tony and Kushnir, Sergei and Zabeau, Marc and Laux, Thomas and Hordsworth, Mike and Ruberti, Ida and Ratcliff, Frank and Smeekens, Sjef and Somssich, Imre and Weisshaar, Bernd and Traas, Jan (2002). REGIA, an EU project on functional genomics of transcription factors from Arabidopsis thaliana. "Comparative and Functional Genomics", v. 3 (n. 2); pp. 102-108. ISSN 1531-6912. https://doi.org/10.1002/cfg.146.

Description

Title: REGIA, an EU project on functional genomics of transcription factors from Arabidopsis thaliana
Author/s:
  • Paz Ares, Javier
  • Valencia, Alfonso
  • Costantino, Paolo
  • Vittorioso, Paola
  • Davies, Brendan
  • Gilmartin, Phil
  • Giraudat, Jerome
  • Parcy, François
  • Reindl, Andreas
  • Sablowski, Robert
  • Coupland, George
  • Martin, Cathie
  • Angenent, Cerco C.
  • Baumlein, Helmut
  • Mock, Hans Peter
  • Carbonero Zalduegui, Pilar
  • Colombo, Lucia
  • Tonelli, Chiara
  • Engström, Peter
  • Dröege-Laser, Wolfgang
  • Gatz, Christiane
  • Kavanagh, Tony
  • Kushnir, Sergei
  • Zabeau, Marc
  • Laux, Thomas
  • Hordsworth, Mike
  • Ruberti, Ida
  • Ratcliff, Frank
  • Smeekens, Sjef
  • Somssich, Imre
  • Weisshaar, Bernd
  • Traas, Jan
Item Type: Article
Título de Revista/Publicación: Comparative and Functional Genomics
Date: March 2002
ISSN: 1531-6912
Volume: 3
Subjects:
Freetext Keywords: REGIA; Arabidopsis; transcription factors; functional genomics; array; twohybrid system; insertion mutant
Faculty: E.T.S. de Ingeniería Agronómica, Alimentaria y de Biosistemas (UPM)
Department: Biotecnología - Biología Vegetal
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

Transcription factors (TFs) are regulatory proteins that have played a pivotal role in the evolution of eukaryotes and that also have great biotechnological potential. REGIA (REgulatory Gene Initiative in Arabidopsis) is an EU-funded project involving 29 European laboratories with the objective of determining the function of virtually all transcription factors from the model plant, Arabidopsis thaliana. REGIA involves: 1. the definition of TF gene expression patterns in Arabidopsis; 2. the identification of mutations at TF loci; 3. the ectopic expression of TFs (or derivatives) in Arabidopsis and in crop plants; 4. phenotypic analysis of the mutants and mis-expression lines, including both RNA and metabolic profiling; 5. the systematic analysis of interactions between TFs; and 6. the generation of a bioinformatics infrastructure to access and integrate all this information. We expect that this programme will establish the full biotechnological potential of plant TFs, and provide insights into hierarchies, redundancies, and interdependencies, and their evolution. The project involves the preparation of both a TF gene array for expression analysis and a normalised full length open reading frame (ORF) library of TFs in a yeast two hybrid vector; the applications of these resources should extend beyond the scope of this programme

Funding Projects

TypeCodeAcronymLeaderTitle
UnspecifiedQLRT-1999-00876REGIAUnspecifiedREgulatory Genes Initiative in Arabidopsis

More information

Item ID: 53742
DC Identifier: http://oa.upm.es/53742/
OAI Identifier: oai:oa.upm.es:53742
DOI: 10.1002/cfg.146
Official URL: https://www.hindawi.com/journals/ijg/2002/302979/abs/
Deposited by: Biblioteca ETSI Agrónomos
Deposited on: 25 Jan 2019 13:30
Last Modified: 13 Jun 2019 11:07
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