Vowel articulation dynamic stability related to Parkinson's disease rating features: male dataset

Gómez Vilda, Pedro and Galaz, Zoltan and Mekyska, Jiri and Ferrández Vicente, José Manuel and Gómez Rodellar, Andrés and Palacios Alonso, Daniel and Smekal, Zdenek and Eliasova, Ilona and Kostalova, Milena and Rektorova, Irena (2018). Vowel articulation dynamic stability related to Parkinson's disease rating features: male dataset. "International Journal of Neural Systems", v. 29 (n. 2); pp. 1-13. ISSN 0129-0657. https://doi.org/10.1142/S0129065718500375.

Description

Title: Vowel articulation dynamic stability related to Parkinson's disease rating features: male dataset
Author/s:
  • Gómez Vilda, Pedro
  • Galaz, Zoltan
  • Mekyska, Jiri
  • Ferrández Vicente, José Manuel
  • Gómez Rodellar, Andrés
  • Palacios Alonso, Daniel
  • Smekal, Zdenek
  • Eliasova, Ilona
  • Kostalova, Milena
  • Rektorova, Irena
Item Type: Article
Título de Revista/Publicación: International Journal of Neural Systems
Date: 2018
ISSN: 0129-0657
Volume: 29
Subjects:
Freetext Keywords: Neurodegenerative disorder; Parkinson’s disease; Speech neuromotor activity; Aging voice; Hypokinetic dysarthria
Faculty: E.T.S. de Ingenieros Informáticos (UPM)
Department: Arquitectura y Tecnología de Sistemas Informáticos
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

Neurodegenerative pathologies as Parkinson's Disease (PD) show important distortions in speech, affecting fluency, prosody, articulation and phonation. Classically, measurements based on articulation gestures altering formant positions, as the Vocal Space Area (VSA) or the Formant Centralization Ratio (FCR) have been proposed to measure speech distortion, but these markers are based mainly on static positions of sustained vowels. The present study introduces a measurement based on the mutual information distance among probability density functions of kinematic correlates derived from formant dynamics. An absolute kinematic velocity associated to the position of the jaw and tongue articulation gestures is estimated and modeled statistically. The distribution of this feature may differentiate PD patients from normative speakers during sustained vowel emission. The study is based on a limited database of 53 male PD patients, contrasted to a very selected and stable set of eight normative speakers. In this sense, distances based on Kullback-Leibler divergence seem to be sensitive to PD articulation instability. Correlation studies show statistically relevant relationship between information contents based on articulation instability to certain motor and nonmotor clinical scores, such as freezing of gait, or sleep disorders. Remarkably, one of the statistically relevant correlations point out to the time interval passed since the first diagnostic. These results stress the need of defining scoring scales specifically designed for speech disability estimation and monitoring methodologies in degenerative diseases of neuromotor origin.

Funding Projects

TypeCodeAcronymLeaderTitle
Government of SpainTEC2016-77791-C4-4-RUnspecifiedUniversidad Politécnica de MadridDescripción biométrica del locutor basada en correlatos de acción motora y estado cognitivo con aplicaciones en seguridad y rehabilitación

More information

Item ID: 54664
DC Identifier: http://oa.upm.es/54664/
OAI Identifier: oai:oa.upm.es:54664
DOI: 10.1142/S0129065718500375
Official URL: https://www.worldscientific.com/doi/pdf/10.1142/S0129065718500375
Deposited by: Memoria Investigacion
Deposited on: 07 May 2019 11:30
Last Modified: 07 May 2019 11:30
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