Rapid detection of pathogens using lyotropic liquid crystals

Otón Martínez, Eva and Otón Sánchez, José Manuel and Caño García, Manuel and Escolano Moyano, José Miguel and Quintana Arregui, Patxi Xabier and Geday, Morten Andreas (2019). Rapid detection of pathogens using lyotropic liquid crystals. "Optics Express", v. 27 (n. 7); pp. 10098-10107. ISSN 1094-4087. https://doi.org/10.1364/OE.27.010098.

Description

Title: Rapid detection of pathogens using lyotropic liquid crystals
Author/s:
  • Otón Martínez, Eva
  • Otón Sánchez, José Manuel
  • Caño García, Manuel
  • Escolano Moyano, José Miguel
  • Quintana Arregui, Patxi Xabier
  • Geday, Morten Andreas
Item Type: Article
Título de Revista/Publicación: Optics Express
Date: 2019
ISSN: 1094-4087
Volume: 27
Subjects:
Faculty: E.T.S.I. Telecomunicación (UPM)
Department: Tecnología Fotónica y Bioingeniería
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

Lyotropic liquid crystals play an important role in many biological environments, such as micelles, liposomes, and phospholipid bilayers of cell membranes. In this work, we explore the performance of lyotropic liquid crystals as biosensors for macromolecules, proteins and whole microorganisms in hydrophilic media, i.e., the natural media where these specimens exist. The aim is to detect specific targets employing simple, unpowered sensors that can be used in the field, with minimum additional equipment. A number of different structures have been explored. The novelty in this work is the inclusion of a new optical effect, flow enhanced amplification, that allows for the semiquantitative detection of microscopic targets in lyotropic liquid crystal cells using the naked eye only.

Funding Projects

TypeCodeAcronymLeaderTitle
Government of SpainTEC2016-77242-C3-2-RRETOSUnspecifiedUnspecified
Government of SpainBES-2014-070964UnspecifiedUnspecifiedUnspecified
Madrid Regional GovernmentS2013/MIT-2790SINFOTON-CMUnspecifiedSensores e instrumentación en tecnologías fotónicas
FP7HEALTH 2012.2.2.3.0UnspecifiedUnspecifiedUnspecified

More information

Item ID: 54955
DC Identifier: http://oa.upm.es/54955/
OAI Identifier: oai:oa.upm.es:54955
DOI: 10.1364/OE.27.010098
Official URL: https://www.osapublishing.org/oe/fulltext.cfm?uri=oe-27-7-10098&id=407704
Deposited by: Memoria Investigacion
Deposited on: 20 May 2019 15:26
Last Modified: 20 May 2019 15:26
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