New dimeric inhibitor of heterologous α-amylases encoded by a duplicated gene in the short arm of chromosome 3B of wheat (Triticum aestivum L.)

Sánchez-Monge Laguna de Rins, Rosa and Gomez Fernandez, Luis and García Olmedo, Francisco and Salcedo Duran, Gabriel (1989). New dimeric inhibitor of heterologous α-amylases encoded by a duplicated gene in the short arm of chromosome 3B of wheat (Triticum aestivum L.). "The FEBS Journal. European Journal of Biochemistry", v. 183 (n. 1); pp. 37-40. https://doi.org/10.1111/j.1432-1033.1989.tb14893.x.

Description

Title: New dimeric inhibitor of heterologous α-amylases encoded by a duplicated gene in the short arm of chromosome 3B of wheat (Triticum aestivum L.)
Author/s:
  • Sánchez-Monge Laguna de Rins, Rosa
  • Gomez Fernandez, Luis
  • García Olmedo, Francisco
  • Salcedo Duran, Gabriel
Item Type: Article
Título de Revista/Publicación: The FEBS Journal. European Journal of Biochemistry
Date: July 1989
Volume: 183
Subjects:
Faculty: E.T.S.I. Agrónomos (UPM) [antigua denominación]
Department: Biotecnologia [hasta 2014]
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

A new wheat dimeric α-amylase inhibitor, designated WDAI-3, has been characterized. WDAI-3 is a homodimeric protein active against α-amylase from human saliva and from the insect Tenebrio molitor, but inactive against that from pig pancreas or against trypsin. Its N-terminal amino acid sequence is closer to those of the wheat dimeric inhibitors 0.19 and 0.53 (89–91% identical positions in 44 residues) than to that of the monomeric 0.28 inhibitor (69% identical positions). Iha-BI-2, the gene encoding the new inhibitor, is located in the short arm of chromosome 3B, where it is part of an intrachromosomal gene duplication that also codes for the 0.53 inhibitor.

More information

Item ID: 5882
DC Identifier: http://oa.upm.es/5882/
OAI Identifier: oai:oa.upm.es:5882
DOI: 10.1111/j.1432-1033.1989.tb14893.x
Official URL: http://onlinelibrary.wiley.com/doi/10.1111/j.1432-1033.1989.tb14893.x/full
Deposited by: Memoria Investigacion
Deposited on: 03 Feb 2011 10:03
Last Modified: 20 Apr 2016 14:34
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