n-3 PUFA Sources (Precursor/Products): A Review of Current Knowledge on Rabbit

Rodríguez, María and Garcia Rebollar, Pilar and Mattioli, Simona and Castellini, Cesare (2019). n-3 PUFA Sources (Precursor/Products): A Review of Current Knowledge on Rabbit. "Animals", v. 9 (n. 10); p. 806. ISSN 2076-2615. https://doi.org/10.3390/ani9100806.

Description

Title: n-3 PUFA Sources (Precursor/Products): A Review of Current Knowledge on Rabbit
Author/s:
  • Rodríguez, María
  • Garcia Rebollar, Pilar
  • Mattioli, Simona
  • Castellini, Cesare
Item Type: Article
Título de Revista/Publicación: Animals
Date: October 2019
ISSN: 2076-2615
Volume: 9
Subjects:
Freetext Keywords: PUFA sources; PUFA metabolism; supplementation; rabbit
Faculty: E.T.S. de Ingeniería Agronómica, Alimentaria y de Biosistemas (UPM)
Department: Producción Agraria
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

This review compares the effects of different n-3 polyunsaturated fatty acid (PUFA) sources on biological activity, physiological/reproductive endpoints, and health implications with a special emphasis on a rabbit case study. Linoleic acid (LA) and α-linolenic acid (ALA) are members of two classes of PUFAs, namely the n-6 and n-3 series, which are required for normal human health. Both are considered precursors of a cascade of molecules (eicosanoids), which take part in many biological processes (inflammation, vasoconstriction/vasodilation, thromboregulation, etc.). However, their biological functions are opposite and are mainly related to the form (precursor or long-chain products) in which they were administered and to the enzyme–substrate preference. ALA is widely present in common vegetable oils and foods, marine algae, and natural herbs, whereas its long-chain PUFA derivatives are available mainly in fish and animal product origins. Recent studies have shown that the accumulation of n-3 PUFAs seems mostly to be tissue-dependent and acts in a tissue-selective manner. Furthermore, dietary n-3 PUFAs widely affect the lipid oxidation susceptibility of all tissues. In conclusion, sustainable sources of n-3 PUFAs are limited and exert a different effect about (1) the form in which they are administered, precursor or derivatives; (2) their antioxidant protections; and (3) the purpose to be achieved (health improvement, physiological and reproductive traits, metabolic pathways, etc.).

Funding Projects

TypeCodeAcronymLeaderTitle
Government of SpainAGL2015-65572-C2-R1UnspecifiedUnspecifiedUnspecified

More information

Item ID: 63657
DC Identifier: http://oa.upm.es/63657/
OAI Identifier: oai:oa.upm.es:63657
DOI: 10.3390/ani9100806
Official URL: https://doi.org/10.3390/ani9100806
Deposited by: Memoria Investigacion
Deposited on: 23 Sep 2020 17:46
Last Modified: 23 Sep 2020 17:46
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