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García-Polo, Pablo and Pajares, Gonzalo and Hernández Tamames, J.A. and Alfayate, E. and Frank, A. and Alvarez Linera, Juan (2011). Changes in the Papez Circuit in early stages of Alzheimer's Disease. In: "Global Alzheimer's Research Summit", 2011, Madrid.
Title: | Changes in the Papez Circuit in early stages of Alzheimer's Disease |
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Author/s: |
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Item Type: | Presentation at Congress or Conference (Poster) |
Event Title: | Global Alzheimer's Research Summit |
Event Dates: | 2011 |
Event Location: | Madrid |
Title of Book: | Global Alzheimer's Research Summit |
Date: | 2011 |
Subjects: | |
Faculty: | Centro de Tecnología Biomédica (CTB) (UPM) |
Department: | Otro |
Creative Commons Licenses: | Recognition - No derivative works - Non commercial |
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Alzheimer's disease (AD) is the most common cause of demenMa. Neuronal and synapMc losses occur iniMally and predominantly in the medial temporal lobe structures including hippocampus, amygdala and thalamus, structures that belong to the Papez circuit. The integrity of the connecMons amongst them is essenMal for episodic memory, which is specifically impaired in AD. For this reason we have invesMgated the degeneraMon paRern of subcorMcal structures and its relaMon to early stages of AD, i.e. Mild CogniMve Impairment (MCI), both in the amnesic and mulMdomain types using structural magneMc resonance imaging (using a 3T GE scanner) and VBM‐DARTEL.
Item ID: | 13589 |
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DC Identifier: | https://oa.upm.es/13589/ |
OAI Identifier: | oai:oa.upm.es:13589 |
Deposited by: | Memoria Investigacion |
Deposited on: | 15 Jan 2013 09:46 |
Last Modified: | 21 Apr 2016 12:55 |