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Angulo Barrios, Carlos and Bañuls, María José and González-Pedro, Victoria and Gylfason, Kristinn B. and Sánchez, Benito and Griol Barres, Amadeu and Maquieira, A. and Sohlström, Hans and Holgado Bolaños, Miguel and Casquel del Campo, Rafael (2008). Label-free optical biosensing with slot-waveguides.. "Optics Letters", v. 33 (n. 7); pp. 708-710. ISSN 0146-9592.
Title: | Label-free optical biosensing with slot-waveguides. |
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Author/s: |
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Item Type: | Article |
Título de Revista/Publicación: | Optics Letters |
Date: | April 2008 |
ISSN: | 0146-9592 |
Volume: | 33 |
Subjects: | |
Faculty: | Instituto de Sistemas Optoelectrónicos y Microtecnología (ISOM) (UPM) |
Department: | Otro |
Creative Commons Licenses: | Recognition - No derivative works - Non commercial |
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We demonstrate label-free molecule detection by using an integrated biosensor based on a Si3N4 /SiO2 slotwaveguide microring resonator. Bovine serum albumin (BSA) and anti-BSA molecular binding events on the sensor surface are monitored through the measurement of resonant wavelength shifts with varying biomolecule concentrations. The biosensor exhibited sensitivities of 1.8 and 3.2 nm/ _ng/mm2_ for the detection of anti-BSA and BSA, respectively. The estimated detection limits are 28 and 16 pg/mm2 for anti-BSA and BSA, respectively, limited by wavelength resolution
Item ID: | 2291 |
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DC Identifier: | https://oa.upm.es/2291/ |
OAI Identifier: | oai:oa.upm.es:2291 |
Official URL: | http://www.opticsinfobase.org/ol/issue.cfm?volume=33&issue=7 |
Deposited by: | Memoria Investigacion |
Deposited on: | 19 Feb 2010 11:17 |
Last Modified: | 09 Mar 2016 12:36 |