Aluminum nanoholes for optical biosensing

Angulo Barrios, Carlos and Canalejas Tejero, Victor and Herranz, Sonia and Urraca, Javier and Moreno Bondi, María Cruz and Avella Oliver, Miquel and Maquieira, Ángel and Puchades, Rosa (2015). Aluminum nanoholes for optical biosensing. "Biosensors", v. 5 (n. 3); pp. 417-431. ISSN 0265-928X.


Title: Aluminum nanoholes for optical biosensing
  • Angulo Barrios, Carlos
  • Canalejas Tejero, Victor
  • Herranz, Sonia
  • Urraca, Javier
  • Moreno Bondi, María Cruz
  • Avella Oliver, Miquel
  • Maquieira, Ángel
  • Puchades, Rosa
Item Type: Article
Título de Revista/Publicación: Biosensors
Date: 2015
ISSN: 0265-928X
Volume: 5
Freetext Keywords: Aluminum; metal nanoholes; nanohole arrays; surface plasmon resonance; optical biosensing; nanopatterning; transfer printing; molecularly imprinted polymer; photopolymerization
Faculty: Instituto de Sistemas Optoelectrónicos y Microtecnología (ISOM) (UPM)
Department: Tecnología Fotónica y Bioingeniería
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Sub-wavelength diameter holes in thin metal layers can exhibit remarkable optical features that make them highly suitable for (bio)sensing applications. Either as efficient light scattering centers for surface plasmon excitation or metal-clad optical waveguides, they are able to form strongly localized optical fields that can effectively interact with biomolecules and/or nanoparticles on the nanoscale. As the metal of choice, aluminum exhibits good optical and electrical properties, is easy to manufacture and process and, unlike gold and silver, its low cost makes it very promising for commercial applications. However, aluminum has been scarcely used for biosensing purposes due to corrosion and pitting issues. In this short review, we show our recent achievements on aluminum nanohole platforms for (bio)sensing. These include a method to circumvent aluminum degradation—which has been successfully applied to the demonstration of aluminum nanohole array (NHA) immunosensors based on both, glass and polycarbonate compact discs supports—the use of aluminum nanoholes operating as optical waveguides for synthesizing submicron-sized molecularly imprinted polymers by local photopolymerization, and a technique for fabricating transferable aluminum NHAs onto flexible pressure-sensitive adhesive tapes, which could facilitate the development of a wearable technology based on aluminum NHAs.

Funding Projects

Government of SpainTEC2012-31145UnspecifiedUnspecifiedUnspecified
Government of SpainCTQ2012-37573-C02UnspecifiedUnspecifiedUnspecified
Government of SpainCTQ 2013-45875-RUnspecifiedUnspecifiedUnspecified

More information

Item ID: 40698
DC Identifier:
OAI Identifier:
DOI: 10.3390/bios5030417
Official URL:
Deposited by: Memoria Investigacion
Deposited on: 05 Sep 2016 16:15
Last Modified: 05 Sep 2016 16:15
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