Assessment of intraoperative 3D imaging alternatives for IOERT dose estimation

García Vázquez, Verónica and Marinetto, Eugenio and Guerra Gutiérrez, Pedro and Valdivieso Casique, Manlio Fabio and Calvo Manuel, Felipe Ángel and Alvarado Vásquez, Eduardo and Solé Pesutic, Claudio Vicente and Vosburgh, Kirby Gannett and Desco Menéndez, Manuel and Pascau González-Garzón, Javier (2017). Assessment of intraoperative 3D imaging alternatives for IOERT dose estimation. "Zeitschrift für Medizinische Physik", v. 27 (n. 3); pp. 218-231. ISSN 0939-3889.


Title: Assessment of intraoperative 3D imaging alternatives for IOERT dose estimation
  • García Vázquez, Verónica
  • Marinetto, Eugenio
  • Guerra Gutiérrez, Pedro
  • Valdivieso Casique, Manlio Fabio
  • Calvo Manuel, Felipe Ángel
  • Alvarado Vásquez, Eduardo
  • Solé Pesutic, Claudio Vicente
  • Vosburgh, Kirby Gannett
  • Desco Menéndez, Manuel
  • Pascau González-Garzón, Javier
Item Type: Article
Título de Revista/Publicación: Zeitschrift für Medizinische Physik
Date: September 2017
ISSN: 0939-3889
Volume: 27
Freetext Keywords: IOERT, radiotherapy, intraoperative imaging, dose distribution
Faculty: E.T.S.I. Telecomunicación (UPM)
Department: Ingeniería Electrónica
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Intraoperative electron radiation therapy (IOERT) involves irradiation of an unresected tumour or a post-resection tumour bed. The dose distribution is calculated from a preoperative computed tomography (CT) study acquired using a CT simulator. However, differences between the actual IOERT field and that calculated from the preoperative study arise as a result of patient position, surgical access, tumour resection and the IOERT set-up. Intraoperative CT imaging may then enable a more accurate estimation of dose distribution. In this study, we evaluated three kilovoltage (kV) CT scanners with the ability to acquire intraoperative images. Our findings indicate that current IOERT plans may be improved using data based on actual anatomical conditions during radiation. The systems studied were two portable systems (“O-arm”, a cone-beam CT [CBCT] system, and “BodyTom”, a multislice CT [MSCT] system) and one CBCT integrated in a conventional linear accelerator (LINAC) (“TrueBeam”). TrueBeam and BodyTom showed good results, as the gamma pass rates of their dose distributions compared to the gold standard (dose distributions calculated from images acquired with a CT simulator) were above 97% in most cases. The O-arm yielded a lower percentage of voxels fulfilling gamma criteria owing to its reduced field of view (which left it prone to truncation artefacts). Our results show that the images acquired using a portable CT or even a LINAC with on-board kV CBCT could be used to estimate the dose of IOERT and improve the possibility to evaluate and register the treatment administered to the patient.

Funding Projects

Government of SpainIPT-2012-0401-300000UnspecifiedUnspecifiedUnspecified
Government of SpainTEC2013-48251-C2-1-RUnspecifiedUnspecifiedUnspecified
Government of SpainDTS14/00192UnspecifiedUnspecifiedUnspecified
Government of SpainPI-15/02121UnspecifiedUnspecifiedUnspecified
Madrid Regional GovernmentS2013/MIT-3024OPUS-CMUnspecifiedCaracterización de centelleadores y SIPM para coincidencias PET. Medidas de resolución temporal y en energía.

More information

Item ID: 50719
DC Identifier:
OAI Identifier:
DOI: 10.1016/j.zemedi.2016.07.002
Official URL:
Deposited by: Memoria Investigacion
Deposited on: 21 May 2018 16:25
Last Modified: 30 Sep 2018 22:30
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