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García-Minguillán López, Olga, Prous, Raquel, Ramírez Castillejo, María del Carmen ORCID: https://orcid.org/0000-0002-1877-3381 and Maestu Unturbe, Ceferino
ORCID: https://orcid.org/0000-0001-8380-1193
(2019).
CT2A cell viability modulated by electromagnetic fields at extremely low frequency under no thermal effects.
"International Journal of Molecular Sciences", v. 21
(n. 1);
pp. 1-13.
ISSN 1661-6596.
https://doi.org/10.3390/ijms21010152.
Title: | CT2A cell viability modulated by electromagnetic fields at extremely low frequency under no thermal effects |
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Author/s: |
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Item Type: | Article |
Título de Revista/Publicación: | International Journal of Molecular Sciences |
Date: | 24 December 2019 |
ISSN: | 1661-6596 |
Volume: | 21 |
Subjects: | |
Freetext Keywords: | ELF-EMF; CT2A; cell viability; HSP90 |
Faculty: | E.T.S.I. Telecomunicación (UPM) |
Department: | Tecnología Fotónica y Bioingeniería |
Creative Commons Licenses: | Recognition - No derivative works - Non commercial |
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The effects produced by electromagnetic fields (EMFs) on human beings at extremely low frequencies (ELFs) have being investigated in the past years, across in vitro studies, using different cell lines. Nevertheless, the effects produced on cells are not clarified, and the cellular mechanisms and cell-signaling processes involved are still unknown. This situation has resulted in a division among the scientific community about the adequacy of the recommended level of exposure. In this sense, we consider that it is necessary to develop long-term exposure studies and check if the recommended levels of EMFs are under thermal effects. Hence, we exposed CT2A cells to different EMFs at different ELFs at short and long times. Our results showed frequency dependence in CT2A exposed during 24 h to a small EMF of 30 ?T equal to those originated by the Earth and frequency dependence after the exposure during seven days to an EMF of 100 µT at different ELFs. Particularly, our results showed a remarkable cell viability decrease of CT2A cells exposed to EMFs of 30 Hz. Nevertheless, after analyzing the thermal effects in terms of HSP90 expression, we did not find thermal damages related to the differences in cell viability, so other crucial cellular mechanism should be involved.
Item ID: | 64253 |
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DC Identifier: | https://oa.upm.es/64253/ |
OAI Identifier: | oai:oa.upm.es:64253 |
DOI: | 10.3390/ijms21010152 |
Official URL: | https://www.mdpi.com/1422-0067/21/1/152 |
Deposited by: | Memoria Investigacion |
Deposited on: | 07 Oct 2020 13:58 |
Last Modified: | 31 Mar 2023 17:08 |