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Armañanzas Arnedillo, Ruben, Alonso Nanclares, Lidia, DeFelipe-Oroquieta, Jesús, Kastanauskaite, Asta, García de Sola, Rafael, DeFelipe, Javier, Bielza Lozoya, María Concepción ORCID: https://orcid.org/0000-0001-7109-2668 and Larrañaga Múgica, Pedro María
ORCID: https://orcid.org/0000-0002-1885-4501
(2013).
Machine learning approach for the outcome prediction of temporal lobe epilepsy surgery.
"Plos One", v. 8
(n. 4);
pp. 1-9.
ISSN 1932-6203.
https://doi.org/10.1371/journal.pone.0062819.
Title: | Machine learning approach for the outcome prediction of temporal lobe epilepsy surgery |
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Author/s: |
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Item Type: | Article |
Título de Revista/Publicación: | Plos One |
Date: | April 2013 |
ISSN: | 1932-6203 |
Volume: | 8 |
Subjects: | |
Faculty: | Facultad de Informática (UPM) |
Department: | Inteligencia Artificial |
Creative Commons Licenses: | Recognition - No derivative works - Non commercial |
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Epilepsy surgery is effective in reducing both the number and frequency of seizures, particularly in temporal lobe epilepsy (TLE). Nevertheless, a significant proportion of these patients continue suffering seizures after surgery. Here we used a machine learning approach to predict the outcome of epilepsy surgery based on supervised classification data mining taking in to account not only the common clinical variables, but also pathological and neuropsychological evaluations. We have generated models capable of predicting whether a patient with TLE secondary to hippocampal sclerosis will fully recover from epilepsy or not. The machine learning analysis revealed that outcome could be predicted with an estimated accuracy of almost 90% using some clinical and neuropsychological features. Importantly, not all the features were needed to perform the prediction; some of them proved to be irrelevant to the prognosis. Personality style was found to be one of the key features to predict the outcome. Although we examined relatively few cases, findings were verified across all data, showing that the machine learning approach described in the present study may be a powerful method. Since neuropsychological assessment of epileptic patients is a standard protocol in the pre-surgical evaluation, we propose to include these specific psychological tests and machine learning tools to improve the selection of candidates for epilepsy surgery.
Item ID: | 72858 |
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DC Identifier: | https://oa.upm.es/72858/ |
OAI Identifier: | oai:oa.upm.es:72858 |
DOI: | 10.1371/journal.pone.0062819 |
Official URL: | https://journals.plos.org/plosone/article?id=10.13... |
Deposited by: | Biblioteca Facultad de Informatica |
Deposited on: | 06 Mar 2023 14:14 |
Last Modified: | 07 Mar 2023 07:12 |