%0 Journal Article %@ 2159-3930 %A Choudhury, B. Dev %A Casquel del Campo, Rafael %A Bañuls, María José %A Sanza Gutiérrez, Francisco Javier %A Laguna Heras, Maria Fe %A Holgado Bolaños, Miguel %A Puchades, Rosa %A Maquieira, Ángel %A Angulo Barrios, Carlos %A Anand, S. %D 2014 %F upm:35593 %I OSA Publishing %J Optical Materials Express %K OCIS codes: (040.6040) Silicon; (110.4235) Nanolithography; (180.3170) Interference microscopy; (220.4241) Nanostructure fabrication; (260.3160) Interference; (280.1415) Biological sensing and sensors; (280.4788) Optical sensing and sensors; (300.6300) Spectroscopy, Fourier transforms; (310.1860) Deposition and fabrication. %N 7 %P 1345-1354 %T Silicon nanopillar arrays with SiO2 overlayer for biosensing application %U https://oa.upm.es/35593/ %V 4 %X We present the fabrication of silicon dioxide (SiO2) coated silicon nanopillar array structures and demonstrate their application as sensitive optical biosensors. Colloidal lithography, plasma dry etching and deposition processes are used to fabricate SiO2 coated Si nanopillar arrays with two different diameters and periods. Proof of concept bio recognition experiments are carried out with the bovine serum albumin (BSA)/antiBSA model system using Fourier transform visible and IR spectrometry (FT-VIS-IR) in reflection mode. A limit of detection (LoD) value of 5.2 ng/ml is estimated taking in to account the wavenumber uncertainty in the measurements.