@article{upm8596,
            year = {2010},
          author = {Jan Tonnesen and Emma Gonzalez Seiz and Milagros Ramos Gomez and Olle Lindval and Alberto Martinez Serrano and Merab Kokaia},
           pages = {653--653},
         journal = {Experimental Neurology},
           title = {Functional properties of the human ventral mesencephalic neural stem cell line hVM1.},
           month = {June},
          number = {2},
          volume = {223},
       publisher = {Elsevier},
        abstract = {The human fetal ventral mesencephalon-derived stem cell line, hVM1, yields high number of tyrosine hydroxylase-expressing presumed dopaminergic neurons upon in vitro differentiation. Here we report that cells generated from this line differentiate into a neuronal phenotype, express electrophysiological properties of functional neurons and respond to neurotransmitters in vitro. However, the electrophysiological properties are immature and the cells require longer maturation time than possible under in vitro conditions},
        keywords = {Human neural stem cell; Dopaminergic neuron; In vitro; Electrophysiology; Functional properties; Differentiation; Parkinson's disease},
             url = {https://oa.upm.es/8596/}
}