TY  - JOUR
IS  - 2
A1  - Tonnesen, Jan
A1  - Gonzalez Seiz, Emma
A1  - Ramos Gomez, Milagros
A1  - Lindval, Olle
A1  - Martinez Serrano, Alberto
A1  - Kokaia, Merab
SN  - 0014-4886
N2  - The human fetal ventral mesencephalon-derived stem cell line, hVM1, yields high number of tyrosine hydroxylase-expressing presumed dopaminergic neurons upon in vitro differentiation. Here we report that cells generated from this line differentiate into a neuronal phenotype, express electrophysiological properties of functional neurons and respond to neurotransmitters in vitro. However, the electrophysiological properties are immature and the cells require longer maturation time than possible under in vitro conditions
JF  - Experimental Neurology
PB  - Elsevier
Y1  - 2010/06//
KW  - Human neural stem cell; Dopaminergic neuron; In vitro; Electrophysiology; Functional properties; Differentiation; Parkinson's disease
EP  - 653
SP  - 653
AV  - public
UR  - http://www.sciencedirect.com/science/journal/00144886
ID  - upm8596
VL  - 223
TI  - Functional properties of the human ventral mesencephalic neural stem cell line hVM1.
ER  -