TY - JOUR IS - 2 A1 - Tonnesen, Jan A1 - Gonzalez Seiz, Emma A1 - Ramos Gomez, Milagros A1 - Lindval, Olle A1 - Martinez Serrano, Alberto A1 - Kokaia, Merab SN - 0014-4886 N2 - The human fetal ventral mesencephalon-derived stem cell line, hVM1, yields high number of tyrosine hydroxylase-expressing presumed dopaminergic neurons upon in vitro differentiation. Here we report that cells generated from this line differentiate into a neuronal phenotype, express electrophysiological properties of functional neurons and respond to neurotransmitters in vitro. However, the electrophysiological properties are immature and the cells require longer maturation time than possible under in vitro conditions JF - Experimental Neurology PB - Elsevier Y1 - 2010/06// KW - Human neural stem cell; Dopaminergic neuron; In vitro; Electrophysiology; Functional properties; Differentiation; Parkinson's disease EP - 653 SP - 653 AV - public UR - http://www.sciencedirect.com/science/journal/00144886 ID - upm8596 VL - 223 TI - Functional properties of the human ventral mesencephalic neural stem cell line hVM1. ER -