Optical Halo: A Proof of Concept for a New Broadband Microrheology Tool

Ramírez García, Jorge ORCID: https://orcid.org/0000-0002-8946-3786, Gibson, Graham ORCID: https://orcid.org/0000-0003-0051-8654 and Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 (2024). Optical Halo: A Proof of Concept for a New Broadband Microrheology Tool. "Micromachines", v. 15 (n. 7); p. 889. ISSN 2072666X. https://doi.org/10.3390/mi15070889.

Descripción

Título: Optical Halo: A Proof of Concept for a New Broadband Microrheology Tool
Autor/es:
Tipo de Documento: Artículo
Título de Revista/Publicación: Micromachines
Fecha: 7 Julio 2024
ISSN: 2072666X
Volumen: 15
Número: 7
Materias:
ODS:
Palabras Clave Informales: Complex fluids; Concentrate Isotropic Solutions; Dynamic; Force; Living Cells; Mechanics; Microrheology; Optical Tweezers; Particle; Rheology; Semiflexible Polymers; Tweezers; Viscoelasticity
Escuela: E.T.S.I. Industriales (UPM)
Departamento: Ingeniería Química Industrial y del Medio Ambiente
Licencias Creative Commons: Reconocimiento

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Resumen

Microrheology, the study of material flow at micron scales, has advanced significantly since Robert Brown's discovery of Brownian motion in 1827. Mason and Weitz's seminal work in 1995 established the foundation for microrheology techniques, enabling the measurement of viscoelastic properties of complex fluids using light-scattering particles. However, existing techniques face limitations in exploring very slow dynamics, crucial for understanding biological systems. Here, we present a proof of concept for a novel microrheology technique called "Optical Halo", which utilises a ring-shaped Bessel beam created by optical tweezers to overcome existing limitations. Through numerical simulations and theoretical analysis, we demonstrate the efficacy of the Optical Halo in probing viscoelastic properties across a wide frequency range, including low-frequency regimes inaccessible to conventional methods. This innovative approach holds promise for elucidating the mechanical behaviour of complex biological fluids.

Proyectos asociados

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Gobierno de España
PID2022-136919NB-C32
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Más información

ID de Registro: 89574
Identificador DC: https://oa.upm.es/89574/
Identificador OAI: oai:oa.upm.es:89574
URL Portal Científico: https://portalcientifico.upm.es/es/ipublic/item/10266310
Identificador DOI: 10.3390/mi15070889
URL Oficial: https://www.mdpi.com/2072-666X/15/7/889
Depositado por: iMarina Portal Científico
Depositado el: 20 Jun 2025 05:54
Ultima Modificación: 20 Jun 2025 05:54