Image Processing Challenges in the Creation of Spatiotemporal Gene Expression Atlases of Developing Embryos

Castro González, Carlos and Luengo Oroz, Miguel Ángel and Douloquin, Louise and Thierry, Savy and Melani, Camilo and Desnoulez, Sophie and Bourgine, Paul and Peyrieras, Nadine and Ledesma Carbayo, María Jesús and Santos Lleo, Andres de (2011). Image Processing Challenges in the Creation of Spatiotemporal Gene Expression Atlases of Developing Embryos. In: "33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2011)", 30/08/2011 - 03/09/2011, Boston, MA, EEUU. ISBN 978-1-4244-4121-1. pp. 6841-6844. https://doi.org/10.1109/IEMBS.2011.6091687.

Description

Title: Image Processing Challenges in the Creation of Spatiotemporal Gene Expression Atlases of Developing Embryos
Author/s:
  • Castro González, Carlos
  • Luengo Oroz, Miguel Ángel
  • Douloquin, Louise
  • Thierry, Savy
  • Melani, Camilo
  • Desnoulez, Sophie
  • Bourgine, Paul
  • Peyrieras, Nadine
  • Ledesma Carbayo, María Jesús
  • Santos Lleo, Andres de
Item Type: Presentation at Congress or Conference (Article)
Event Title: 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2011)
Event Dates: 30/08/2011 - 03/09/2011
Event Location: Boston, MA, EEUU
Title of Book: Proceedings of 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2011)
Date: 2011
ISBN: 978-1-4244-4121-1
Subjects:
Faculty: E.T.S.I. Telecomunicación (UPM)
Department: Ingeniería Electrónica
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

To properly understand and model animal embryogenesis it is crucial to obtain detailed measurements, both in time and space, about their gene expression domains and cell dynamics. Such challenge has been confronted in recent years by a surge of atlases which integrate a statistically relevant number of different individuals to get robust, complete information about their spatiotemporal locations of gene patterns. This paper will discuss the fundamental image analysis strategies required to build such models and the most common problems found along the way. We also discuss the main challenges and future goals in the field.

More information

Item ID: 12046
DC Identifier: http://oa.upm.es/12046/
OAI Identifier: oai:oa.upm.es:12046
DOI: 10.1109/IEMBS.2011.6091687
Official URL: http://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=6091687
Deposited by: Memoria Investigacion
Deposited on: 17 Sep 2012 10:47
Last Modified: 21 Apr 2016 11:12
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