Applicability of the GP Device to the Circle of Willis Arteries by Using a Mathematical Model

Romero Rey, Gregorio and Martínez Muneta, María Luisa and Félez Mindán, Jesús and Pearce, Gillian and Perkinson, N.D. (2011). Applicability of the GP Device to the Circle of Willis Arteries by Using a Mathematical Model. In: "2011 UkSim 13th International Conference on Computer Modelling and Simulation (UKSim)", 30/03/2011 - 01/04/2011, Cambridge, United Kingdom. ISBN 978-1-61284-705-4. pp. 48-53.

Description

Title: Applicability of the GP Device to the Circle of Willis Arteries by Using a Mathematical Model
Author/s:
  • Romero Rey, Gregorio
  • Martínez Muneta, María Luisa
  • Félez Mindán, Jesús
  • Pearce, Gillian
  • Perkinson, N.D.
Item Type: Presentation at Congress or Conference (Article)
Event Title: 2011 UkSim 13th International Conference on Computer Modelling and Simulation (UKSim)
Event Dates: 30/03/2011 - 01/04/2011
Event Location: Cambridge, United Kingdom
Title of Book: Proceedings of 2011 UkSim 13th International Conference on Computer Modelling and Simulation (UKSim)
Date: 2011
ISBN: 978-1-61284-705-4
Subjects:
Faculty: E.T.S.I. Industriales (UPM)
Department: Ingeniería Mecánica y de Fabricación [hasta 2014]
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

According to the World Health Organization, 15 million people suffer stroke worldwide each year, of these, 5 million die and 5 million are permanently disabled. Stroke is therefore a major cause of mortality world-wide. The majority of strokes are caused by a blood clot that occludes an artery in the brain, and although thrombolytic agents such as Alteplase are used to dissolve clots that arise in the arteries of the brain, there are limitations on the use of these thrombolytic agents. However over the past decade, other methods of treatment have been developed which include Thrombectomy Devices e.g. the 'GP' Thrombus Aspiration Device ('GP' TAD). Such devices may be used as an alternative to thrombolytics or in conjunction with them to extract blood clots in arteries such as the middle cerebral artery of the midbrain brain, and the posterior inferior cerebellar artery (PICA) of the posterior aspect of the brain. In this paper, we mathematically model the removal of blood clots using the 'GP' TAD from selected arteries of the brain where blood clots may arise taking into account factors such as the resistances, compliances and inertances effects. Such mathematical modelling may have potential uses in predicting the pressures necessary to extract blood clots of given lengths, and masses from arteries in the Circle of Willis - posterior circulation of the brain

More information

Item ID: 12996
DC Identifier: http://oa.upm.es/12996/
OAI Identifier: oai:oa.upm.es:12996
Official URL: http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=5754206
Deposited by: Memoria Investigacion
Deposited on: 11 Dec 2012 11:19
Last Modified: 15 Jun 2017 16:08
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