An Automatic Quantification and Registration Strategy to Create a Gene Expression Atlas of Zebrafish Embryogenesis

Castro González, Carlos and Luengo Oroz, Miguel Ángel and Fernández de Manuel, Laura and Ledesma Carbayo, María Jesús and Santos Lleo, Andres de and Desnoulez, Sophie and Duloquin, Louise and Montagna, Sara and Bourgine, Paul and Peyrieras, Nadine (2009). An Automatic Quantification and Registration Strategy to Create a Gene Expression Atlas of Zebrafish Embryogenesis. In: "31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2009)", 02/06/2009 - 06/06/2009, Minneapolis MN USA. pp. 1469-1472. https://doi.org/10.1109/IEMBS.2009.5332436.

Description

Title: An Automatic Quantification and Registration Strategy to Create a Gene Expression Atlas of Zebrafish Embryogenesis
Author/s:
  • Castro González, Carlos
  • Luengo Oroz, Miguel Ángel
  • Fernández de Manuel, Laura
  • Ledesma Carbayo, María Jesús
  • Santos Lleo, Andres de
  • Desnoulez, Sophie
  • Duloquin, Louise
  • Montagna, Sara
  • Bourgine, Paul
  • Peyrieras, Nadine
Item Type: Presentation at Congress or Conference (Article)
Event Title: 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2009)
Event Dates: 02/06/2009 - 06/06/2009
Event Location: Minneapolis MN USA
Title of Book: Proceedings of Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE
Date: 2009
Subjects:
Faculty: E.T.S.I. Telecomunicación (UPM)
Department: Ingeniería Electrónica
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

In order to properly understand and model the gene regulatory networks in animals development, it is crucial to obtain detailed measurements, both in time and space, about their gene expression domains. In this paper, we propose a complete computational framework to fulfill this task and create a 3D Atlas of the early zebrafish embryogenesis annotated with both the cellular localizations and the level of expression of different genes at different developmental stages. The strategy to construct such an Atlas is described here with the expression pattern of 5 different genes at 6 hours of development post fertilization.

More information

Item ID: 13889
DC Identifier: http://oa.upm.es/13889/
OAI Identifier: oai:oa.upm.es:13889
DOI: 10.1109/IEMBS.2009.5332436
Deposited by: Memoria Investigacion
Deposited on: 25 Feb 2013 08:23
Last Modified: 21 Apr 2016 13:19
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