OPPL-Galaxy, a Galaxy tool for enhancing ontology exploitation as part of bioinformatics workflows

Egaña Aranguren, Mikel; Fernández-Breis, Jesualdo Tomás; Mungall, C.; Antezana, E.; Rodríguez González, A. y Wilkinson, M. (2013). OPPL-Galaxy, a Galaxy tool for enhancing ontology exploitation as part of bioinformatics workflows. "Journal of Biomedical Semantics" ;

Descripción

Título: OPPL-Galaxy, a Galaxy tool for enhancing ontology exploitation as part of bioinformatics workflows
Autor/es:
  • Egaña Aranguren, Mikel
  • Fernández-Breis, Jesualdo Tomás
  • Mungall, C.
  • Antezana, E.
  • Rodríguez González, A.
  • Wilkinson, M.
Tipo de Documento: Artículo
Título de Revista/Publicación: Journal of Biomedical Semantics
Fecha: 4 Enero 2013
Materias:
Escuela: Facultad de Informática (UPM) [antigua denominación]
Departamento: Inteligencia Artificial
Grupo Investigación UPM: oeg
Licencias Creative Commons: Ninguna

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URL Oficial: http://www.jbiomedsem.com/content/4/1/2

Resumen

Biomedical ontologies are key elements for building up the Life Sciences Semantic Web. Reusing and building biomedical ontologies requires flexible and versatile tools to manipulate them efficiently, in particular for enriching their axiomatic content. The Ontology Pre Processor Language (OPPL) is an OWL-based language for automating the changes to be performed in an ontology. OPPL augments the ontologists’ toolbox by providing a more efficient, and less error-prone, mechanism for enriching a biomedical ontology than that obtained by a manual treatment. Results We present OPPL-Galaxy, a wrapper for using OPPL within Galaxy. The functionality delivered by OPPL (i.e. automated ontology manipulation) can be combined with the tools and workflows devised within the Galaxy framework, resulting in an enhancement of OPPL. Use cases are provided in order to demonstrate OPPL-Galaxy’s capability for enriching, modifying and querying biomedical ontologies. Conclusions Coupling OPPL-Galaxy with other bioinformatics tools of the Galaxy framework results in a system that is more than the sum of its parts. OPPL-Galaxy opens a new dimension of analyses and exploitation of biomedical ontologies, including automated reasoning, paving the way towards advanced biological data analyses.

Más información

ID de Registro: 15232
Identificador DC: http://oa.upm.es/15232/
Identificador OAI: oai:oa.upm.es:15232
Depositado por: Dr Oscar Corcho
Depositado el: 10 May 2013 05:50
Ultima Modificación: 21 Abr 2016 15:16
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