Dysfunctional and compensatory duality in mild cognitive impairment during a continuous recognition memory task

Bajo Breton, Ricardo (2012). Dysfunctional and compensatory duality in mild cognitive impairment during a continuous recognition memory task. "International Journal of Psychophysiology", v. 87 (n. 1); pp. 95-102. ISSN 0167-8760. https://doi.org/10.1016/j.ijpsycho.2012.11.008.

Descripción

Título: Dysfunctional and compensatory duality in mild cognitive impairment during a continuous recognition memory task
Autor/es:
  • Bajo Breton, Ricardo
Tipo de Documento: Artículo
Título de Revista/Publicación: International Journal of Psychophysiology
Fecha: 2012
Volumen: 87
Materias:
Escuela: Centro de Tecnología Biomédica (CTB) (UPM)
Departamento: Otro
Licencias Creative Commons: Reconocimiento - Sin obra derivada - No comercial

Texto completo

[img]
Vista Previa
PDF (Document Portable Format) - Se necesita un visor de ficheros PDF, como GSview, Xpdf o Adobe Acrobat Reader
Descargar (3MB) | Vista Previa

Resumen

One of the current issues of debate in the study of mild cognitive impairment (MCI) is deviations of oscillatory brain responses from normal brain states and its dynamics. This work aims to characterize the differences of power in brain oscillations during the execution of a recognition memory task in MCI subjects in comparison with elderly controls. Magnetoencephalographic (MEG) signals were recorded during a continuous recognition memory task performance. Oscillatory brain activity during the recognition phase of the task was analyzed by wavelet transform in the source space by means of minimum norm algorithm. Both groups obtained a 77% hit ratio. In comparison with healthy controls, MCI subjects showed increased theta (p < 0.001), lower beta reduction (p < 0.001) and decreased alpha and gamma power (p < 0.002 and p < 0.001 respectively) in frontal, temporal and parietal areas during early and late latencies. Our results point towards a dual pattern of activity (increase and decrease) which is indicative of MCI and specific to certain time windows, frequency bands and brain regions. These results could represent two neurophysiological sides of MCI. Characterizing these opposing processes may contribute to the understanding of the disorder.

Más información

ID de Registro: 15262
Identificador DC: http://oa.upm.es/15262/
Identificador OAI: oai:oa.upm.es:15262
Identificador DOI: 10.1016/j.ijpsycho.2012.11.008
URL Oficial: http://www.sciencedirect.com/science/article/pii/S016787601200668X
Depositado por: Memoria Investigacion
Depositado el: 20 Sep 2013 18:23
Ultima Modificación: 21 Abr 2016 15:18
  • Open Access
  • Open Access
  • Sherpa-Romeo
    Compruebe si la revista anglosajona en la que ha publicado un artículo permite también su publicación en abierto.
  • Dulcinea
    Compruebe si la revista española en la que ha publicado un artículo permite también su publicación en abierto.
  • Recolecta
  • e-ciencia
  • Observatorio I+D+i UPM
  • OpenCourseWare UPM