Insect growth regulators as potential insecticides to control olive fruit fly (Bactrocera oleae Rossi): insect toxicity bioassays and molecular docking approach

Bengochea Budia, Paloma and Christiaens, Olivier and Amor Parrilla, Fermín and Viñuela Sandoval, Elisa and Rougé, Pierre and Medina Velez, Maria Pilar and Smagghe, Guy (2013). Insect growth regulators as potential insecticides to control olive fruit fly (Bactrocera oleae Rossi): insect toxicity bioassays and molecular docking approach. "Pest Management Science", v. 69 (n. 1); pp. 27-34. ISSN 1526-498X. https://doi.org/10.1002/ps.3350.

Description

Title: Insect growth regulators as potential insecticides to control olive fruit fly (Bactrocera oleae Rossi): insect toxicity bioassays and molecular docking approach
Author/s:
  • Bengochea Budia, Paloma
  • Christiaens, Olivier
  • Amor Parrilla, Fermín
  • Viñuela Sandoval, Elisa
  • Rougé, Pierre
  • Medina Velez, Maria Pilar
  • Smagghe, Guy
Item Type: Article
Título de Revista/Publicación: Pest Management Science
Date: January 2013
ISSN: 1526-498X
Volume: 69
Subjects:
Faculty: E.T.S.I. Agrónomos (UPM) [antigua denominación]
Department: Producción Vegetal: Botánica y Protección Vegetal [hasta 2014]
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

Olive fruit fly, Bactrocera oleae (Rossi), is a key pest in olive orchards, causing serious economic damage. To date, the pest has already developed resistance to the insecticides commonly applied to control it. Thus, in searching for new products for an accurate resistance management programme, targeting the ecdysone receptor (EcR)might provide alternative compounds for use in such programmes. RESULTS: Residual contact and oral exposure in the laboratory of B. oleae adults to the dibenzoylhydrazine-based compounds methoxyfenozide, tebufenozide and RH-5849 showed different results. Methoxyfenozide and tebufenozide did not provoke anynegative effectsontheadults,but RH-5849 killed98-100%of the treated insects15 days after treatment. Theligand-binding domain (LBD) of the EcR of B. oleae (BoEcR-LBD) was sequenced, and a homology protein model was constructed. Owing to a restricted extent of the ligand-binding cavity of the BoEcR-LBD, docking experiments with the three tested insecticides showed a severe steric clash in the case of methoxyfenozide and tebufenozide, while this was not the case with RH-5849. CONCLUSION: IGR molecules similar to the RH-5849 molecule, and different from methoxyfenozide and tebufenozide, might have potential in controlling this pest.

More information

Item ID: 19004
DC Identifier: http://oa.upm.es/19004/
OAI Identifier: oai:oa.upm.es:19004
DOI: 10.1002/ps.3350
Official URL: http://onlinelibrary.wiley.com/doi/10.1002/ps.3350/abstract
Deposited by: Memoria Investigacion
Deposited on: 09 Sep 2013 14:12
Last Modified: 21 Apr 2016 17:14
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