Age-Related Effects in Working Memory Recognition Modulated by Retroactive Interference

Solesio-Jofre, Elena and Lorenzo-López, Laura and Gutierrez, Ricardo and López-Frutos, José María and Ruiz Vargas, Jose Maria and Maestú, Fernando (2012). Age-Related Effects in Working Memory Recognition Modulated by Retroactive Interference. "The Journals of Gerontology: Series A - Biological Sciences And Medical Sciences", v. 67A (n. 6); pp. 565-572. ISSN 1079-5006. https://doi.org/10.1093/gerona/glr199.

Description

Title: Age-Related Effects in Working Memory Recognition Modulated by Retroactive Interference
Author/s:
  • Solesio-Jofre, Elena
  • Lorenzo-López, Laura
  • Gutierrez, Ricardo
  • López-Frutos, José María
  • Ruiz Vargas, Jose Maria
  • Maestú, Fernando
Item Type: Article
Título de Revista/Publicación: The Journals of Gerontology: Series A - Biological Sciences And Medical Sciences
Date: June 2012
ISSN: 1079-5006
Volume: 67A
Subjects:
Faculty: Centro de Tecnología Biomédica (CTB) (UPM)
Department: Otro
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

One of the main causes for age-related declines in working memory is a higher vulnerability to retroactive interference due to a reduced ability to suppress irrelevant information. However, the underlying neural correlates remain to be established. Magnetoencephalography was used to investigate differential neural patterns in young and older adults performing an interference-based memory task with two experimental conditions, interrupting and distracting, during successful recognition. Behaviorally, both types of retroactive interference significantly impaired accuracy at recognition more in older adults than in young adults with the latter exhibiting greater disruptions by interrupters. Magnetoencephalography revealed the presence of differential age-related neural patterns. Specifically, time-modulated activations in temporo-occipital and superior parietal regions were higher in young adults compared with older adults for the interrupting condition. These results suggest that age-related deficits in inhibitory mechanisms that increase vulnerability to retroactive interference may be associated with neural under-recruitments in a high-interference task.

More information

Item ID: 20191
DC Identifier: http://oa.upm.es/20191/
OAI Identifier: oai:oa.upm.es:20191
DOI: 10.1093/gerona/glr199
Official URL: http://biomedgerontology.oxfordjournals.org/content/67A/6/565.abstract
Deposited by: Memoria Investigacion
Deposited on: 14 Oct 2013 14:38
Last Modified: 21 Apr 2016 22:42
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