Merging person-specific bio-markers for predicting oral cancer recurrence through an ontology

Salvi, Dario; Picone, Marco; Arredondo Waldmeyer, Maria Teresa; Cabrera Umpierrez, Maria Fernanda; Esteban, Ángel; Steger, Sebastian y Poli, Tito (2013). Merging person-specific bio-markers for predicting oral cancer recurrence through an ontology. "IEEE Transactions on Biomedical Engineering", v. 60 (n. 1); pp. 216-220. ISSN 0018-9294. https://doi.org/10.1109/TBME.2012.2216879.

Descripción

Título: Merging person-specific bio-markers for predicting oral cancer recurrence through an ontology
Autor/es:
  • Salvi, Dario
  • Picone, Marco
  • Arredondo Waldmeyer, Maria Teresa
  • Cabrera Umpierrez, Maria Fernanda
  • Esteban, Ángel
  • Steger, Sebastian
  • Poli, Tito
Tipo de Documento: Artículo
Título de Revista/Publicación: IEEE Transactions on Biomedical Engineering
Fecha: Enero 2013
Volumen: 60
Materias:
Escuela: E.T.S.I. Telecomunicación (UPM)
Departamento: Tecnología Fotónica [hasta 2014]
Licencias Creative Commons: Reconocimiento - Sin obra derivada - No comercial

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Resumen

One of the major problems related to cancer treatment is its recurrence. Without knowing in advance how likely the cancer will relapse, clinical practice usually recommends adjuvant treatments that have strong side effects. A way to optimize treatments is to predict the recurrence probability by analyzing a set of bio-markers. The NeoMark European project has identified a set of preliminary bio-markers for the case of oral cancer by collecting a large series of data from genomic, imaging, and clinical evidence. This heterogeneous set of data needs a proper representation in order to be stored, computed, and communicated efficiently. Ontologies are often considered the proper mean to integrate biomedical data, for their high level of formality and for the need of interoperable, universally accepted models. This paper presents the NeoMark system and how an ontology has been designed to integrate all its heterogeneous data. The system has been validated in a pilot in which data will populate the ontology and will be made public for further research.

Más información

ID de Registro: 21458
Identificador DC: http://oa.upm.es/21458/
Identificador OAI: oai:oa.upm.es:21458
Identificador DOI: 10.1109/TBME.2012.2216879
URL Oficial: http://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=6293868
Depositado por: Memoria Investigacion
Depositado el: 11 Nov 2013 17:57
Ultima Modificación: 21 Abr 2016 12:03
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