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Stoichiometric analysis of self-maintaining metabolisms
Cita
Montero, Francisco, Sanz Nuño, Juan Carlos 
ORCID: https://orcid.org/0000-0003-4708-980X, Meléndez-Hévia, Enrique, Olasagasti, Félix, Vázquez, Sara and Morán, Federico
(2008).
Stoichiometric analysis of self-maintaining metabolisms.
"Journal of Theoretical Biology", v. 252
(n. 3);
pp. 427-432.
ISSN 0022-5193.
https://doi.org/10.1016/j.jtbi.2007.11.02.
ORCID: https://orcid.org/0000-0003-4708-980X, Meléndez-Hévia, Enrique, Olasagasti, Félix, Vázquez, Sara and Morán, Federico
(2008).
Stoichiometric analysis of self-maintaining metabolisms.
"Journal of Theoretical Biology", v. 252
(n. 3);
pp. 427-432.
ISSN 0022-5193.
https://doi.org/10.1016/j.jtbi.2007.11.02.
Descripción
| Título: | Stoichiometric analysis of self-maintaining metabolisms |
|---|---|
| Autor/es: |
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| Tipo de Documento: | Artículo |
| Título de Revista/Publicación: | Journal of Theoretical Biology |
| Fecha: | Junio 2008 |
| ISSN: | 0022-5193 |
| Volumen: | 252 |
| Número: | 3 |
| Materias: | |
| ODS: | |
| Palabras Clave Informales: | Stoichiometric analysis; Self-maintaining systems; Metabolic networks |
| Escuela: | E.T.S.I. Montes (UPM) [antigua denominación] |
| Departamento: | Matemática Aplicada a los Recursos Naturales [hasta 2014] |
| Licencias Creative Commons: | Reconocimiento - Sin obra derivada - No comercial |
Resumen
This paper presents an extension of stoichiometric analysis in systems where the catalytic compounds (enzymes) are also intermediates of the metabolic network (dual property), so they are produced and degraded by the reaction network itself. To take this property into account, we introduce the definition of enzyme-maintaining mode, a set of reactions that produces its own catalyst and can operate at stationary state. Moreover, an enzyme-maintaining mode is defined as elementary with respect to a given reaction if the removal of any of the remaining reactions causes the cessation of any steady state flux through this reference reaction. These concepts are applied to determine the network structure of a simple self-maintaining system.
Más información
| ID de Registro: | 2202 |
|---|---|
| Identificador DC: | https://oa.upm.es/2202/ |
| Identificador OAI: | oai:oa.upm.es:2202 |
| Identificador DOI: | 10.1016/j.jtbi.2007.11.02 |
| URL Oficial: | http://www.sciencedirect.com/science?_ob=Publicati... |
| Depositado por: | Memoria Investigacion |
| Depositado el: | 03 Mar 2010 12:53 |
| Ultima Modificación: | 20 Abr 2016 11:57 |
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