Label-free optical biosensing with slot-waveguides.

Angulo Barrios, Carlos and Bañuls, María José and González-Pedro, Victoria and Gylfason, Kristinn B. and Sánchez, Benito and Griol Barres, Amadeu and Maquieira, A. and Sohlström, Hans and Holgado Bolaños, Miguel and Casquel del Campo, Rafael (2008). Label-free optical biosensing with slot-waveguides.. "Optics Letters", v. 33 (n. 7); pp. 708-710. ISSN 0146-9592.

Description

Title: Label-free optical biosensing with slot-waveguides.
Author/s:
  • Angulo Barrios, Carlos
  • Bañuls, María José
  • González-Pedro, Victoria
  • Gylfason, Kristinn B.
  • Sánchez, Benito
  • Griol Barres, Amadeu
  • Maquieira, A.
  • Sohlström, Hans
  • Holgado Bolaños, Miguel
  • Casquel del Campo, Rafael
Item Type: Article
Título de Revista/Publicación: Optics Letters
Date: April 2008
ISSN: 0146-9592
Volume: 33
Subjects:
Faculty: Instituto de Sistemas Optoelectrónicos y Microtecnología (ISOM) (UPM)
Department: Otro
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

We demonstrate label-free molecule detection by using an integrated biosensor based on a Si3N4 /SiO2 slotwaveguide microring resonator. Bovine serum albumin (BSA) and anti-BSA molecular binding events on the sensor surface are monitored through the measurement of resonant wavelength shifts with varying biomolecule concentrations. The biosensor exhibited sensitivities of 1.8 and 3.2 nm/ _ng/mm2_ for the detection of anti-BSA and BSA, respectively. The estimated detection limits are 28 and 16 pg/mm2 for anti-BSA and BSA, respectively, limited by wavelength resolution

More information

Item ID: 2291
DC Identifier: http://oa.upm.es/2291/
OAI Identifier: oai:oa.upm.es:2291
Official URL: http://www.opticsinfobase.org/ol/issue.cfm?volume=33&issue=7
Deposited by: Memoria Investigacion
Deposited on: 19 Feb 2010 11:17
Last Modified: 09 Mar 2016 12:36
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