Angulo Barrios, Carlos and Bañuls, María José and González-Pedro, Victoria and Gylfason, Kristinn B. and Sánchez, Benito and Griol, Amadeu and Maquieira, A. and Sohlström, Hans and Holgado Bolaños, Miguel and Casquel Del Campo, Rafael (2008) Label-free optical biosensing with slot-waveguides. Optics Letters, 33 (7). 708 - 710. ISSN 0146-9592
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| Title: | Label-free optical biosensing with slot-waveguides. | ||||||||||||||||||||||
| Publisher: | Optical Society of America | ||||||||||||||||||||||
| Journal/Publication Title: | Optics Letters | ||||||||||||||||||||||
| Date: | April 2008 | ||||||||||||||||||||||
| Volume: | 33 | ||||||||||||||||||||||
| Number: | 7 | ||||||||||||||||||||||
| Department: | Applied Physics Industrial Engineering | ||||||||||||||||||||||
| Faculty: | E.T.S. Architecture (UPM) | ||||||||||||||||||||||
| Creative Commons licenses: | Recognition - No derivative works - No commercial | ||||||||||||||||||||||
| Item ID: | 2291 | ||||||||||||||||||||||
| Subjects: | Materials |
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| PDF 291Kb - Idioma: English |
Official URL: http://www.opticsinfobase.org/ol/issue.cfm?volume=33&issue=7
Abstract
We demonstrate label-free molecule detection by using an integrated biosensor based on a Si3N4 /SiO2 slotwaveguide microring resonator. Bovine serum albumin (BSA) and anti-BSA molecular binding events on the sensor surface are monitored through the measurement of resonant wavelength shifts with varying biomolecule concentrations. The biosensor exhibited sensitivities of 1.8 and 3.2 nm/ _ng/mm2_ for the detection of anti-BSA and BSA, respectively. The estimated detection limits are 28 and 16 pg/mm2 for anti-BSA and BSA, respectively, limited by wavelength resolution
| Item Type: | Article |
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| Subjects: | Materials |
| Código ID: | 2291 |
| Depositado Por: | Memoria Investigacion |
| Depositado el: | 19 Feb 2010 12:17 |
| Last Modified: | 22 Nov 2010 12:09 |
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