Branching angles of pyramidal cell dendrites follow common geometrical design principles in different cortical areas

Bielza Lozoya, Maria Concepcion and Benavides Piccione, Ruth and López Cruz, Pedro Luis and Larrañaga Múgica, Pedro and Felipe Oroquieta, Javier de (2014). Branching angles of pyramidal cell dendrites follow common geometrical design principles in different cortical areas. "Scientific Reports", v. 4 (n. 5909); pp. 1-7. ISSN 2045-2322. https://doi.org/10.1038/srep05909.

Description

Title: Branching angles of pyramidal cell dendrites follow common geometrical design principles in different cortical areas
Author/s:
  • Bielza Lozoya, Maria Concepcion
  • Benavides Piccione, Ruth
  • López Cruz, Pedro Luis
  • Larrañaga Múgica, Pedro
  • Felipe Oroquieta, Javier de
Item Type: Article
Título de Revista/Publicación: Scientific Reports
Date: August 2014
ISSN: 2045-2322
Volume: 4
Subjects:
Faculty: E.T.S. de Ingenieros Informáticos (UPM)
Department: Inteligencia Artificial
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

Unraveling pyramidal cell structure is crucial to understanding cortical circuit computations. Although it is well known that pyramidal cell branching structure differs in the various cortical areas, the principles that determine the geometric shapes of these cells are not fully understood. Here we analyzed and modeled with a von Mises distribution the branching angles in 3D reconstructed basal dendritic arbors of hundreds of intracellularly injected cortical pyramidal cells in seven different cortical regions of the frontal, parietal, and occipital cortex of the mouse. We found that, despite the differences in the structure of the pyramidal cells in these distinct functional and cytoarchitectonic cortical areas, there are common design principles that govern the geometry of dendritic branching angles of pyramidal cells in all cortical areas.

More information

Item ID: 35441
DC Identifier: http://oa.upm.es/35441/
OAI Identifier: oai:oa.upm.es:35441
DOI: 10.1038/srep05909
Official URL: http://www.nature.com/srep/index.html
Deposited by: Memoria Investigacion
Deposited on: 09 Jun 2015 12:49
Last Modified: 14 Jul 2015 09:03
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