Past, present and future of epigenetics applied to livestock breeding

González Recio, Óscar; Toro Ibañez, Miguel Angel y Bach, Alex (2015). Past, present and future of epigenetics applied to livestock breeding. "Frontiers in genetics Journal" ; p. 305. ISSN 1664-8021. https://doi.org/10.3389/fgene.2015.00305.

Descripción

Título: Past, present and future of epigenetics applied to livestock breeding
Autor/es:
  • González Recio, Óscar
  • Toro Ibañez, Miguel Angel
  • Bach, Alex
Tipo de Documento: Artículo
Título de Revista/Publicación: Frontiers in genetics Journal
Fecha: 2015
Materias:
Escuela: E.T.S.I. Agrónomos (UPM) [antigua denominación]
Departamento: Producción Agraria
Licencias Creative Commons: Reconocimiento - Sin obra derivada - No comercial

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Resumen

This article reviews the concept of Lamarckian inheritance and the use of the term epigenetics in the field of animal genetics. Epigenetics was first coined by Conrad Hal Waddington (1905–1975), who derived the term from the Aristotelian word epigenesis. There exists some controversy around the word epigenetics and its broad definition. It includes any modification of the expression of genes due to factors other than mutation in the DNA sequence. This involves DNA methylation, post-translational modification of histones, but also linked to regulation of gene expression by non-coding RNAs, genome instabilities or any other force that could modify a phenotype. There is little evidence of the existence of transgenerational epigenetic inheritance in mammals, which may commonly be confounded with environmental forces acting simultaneously on an individual, her developing fetus and the germ cell lines of the latter, although it could have an important role in the cellular energetic status of cells. Finally, we review some of the scarce literature on the use of epigenetics in animal breeding programs.

Más información

ID de Registro: 40902
Identificador DC: http://oa.upm.es/40902/
Identificador OAI: oai:oa.upm.es:40902
Identificador DOI: 10.3389/fgene.2015.00305
URL Oficial: http://journal.frontiersin.org/article/10.3389/fgene.2015.00305/full
Depositado por: Memoria Investigacion
Depositado el: 08 Jul 2016 15:17
Ultima Modificación: 08 Jul 2016 15:17
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