Past, present and future of epigenetics applied to livestock breeding

González Recio, Óscar and Toro Ibañez, Miguel Angel and Bach, Alex (2015). Past, present and future of epigenetics applied to livestock breeding. "Frontiers in genetics Journal" ; p. 305. ISSN 1664-8021. https://doi.org/10.3389/fgene.2015.00305.

Description

Title: Past, present and future of epigenetics applied to livestock breeding
Author/s:
  • González Recio, Óscar
  • Toro Ibañez, Miguel Angel
  • Bach, Alex
Item Type: Article
Título de Revista/Publicación: Frontiers in genetics Journal
Date: 2015
ISSN: 1664-8021
Subjects:
Faculty: E.T.S.I. Agrónomos (UPM) [antigua denominación]
Department: Producción Agraria
Creative Commons Licenses: Recognition - No derivative works - Non commercial

Full text

[img]
Preview
PDF - Requires a PDF viewer, such as GSview, Xpdf or Adobe Acrobat Reader
Download (195kB) | Preview

Abstract

This article reviews the concept of Lamarckian inheritance and the use of the term epigenetics in the field of animal genetics. Epigenetics was first coined by Conrad Hal Waddington (1905–1975), who derived the term from the Aristotelian word epigenesis. There exists some controversy around the word epigenetics and its broad definition. It includes any modification of the expression of genes due to factors other than mutation in the DNA sequence. This involves DNA methylation, post-translational modification of histones, but also linked to regulation of gene expression by non-coding RNAs, genome instabilities or any other force that could modify a phenotype. There is little evidence of the existence of transgenerational epigenetic inheritance in mammals, which may commonly be confounded with environmental forces acting simultaneously on an individual, her developing fetus and the germ cell lines of the latter, although it could have an important role in the cellular energetic status of cells. Finally, we review some of the scarce literature on the use of epigenetics in animal breeding programs.

More information

Item ID: 40902
DC Identifier: http://oa.upm.es/40902/
OAI Identifier: oai:oa.upm.es:40902
DOI: 10.3389/fgene.2015.00305
Official URL: http://journal.frontiersin.org/article/10.3389/fgene.2015.00305/full
Deposited by: Memoria Investigacion
Deposited on: 08 Jul 2016 15:17
Last Modified: 08 Jul 2016 15:17
  • Logo InvestigaM (UPM)
  • Logo GEOUP4
  • Logo Open Access
  • Open Access
  • Logo Sherpa/Romeo
    Check whether the anglo-saxon journal in which you have published an article allows you to also publish it under open access.
  • Logo Dulcinea
    Check whether the spanish journal in which you have published an article allows you to also publish it under open access.
  • Logo de Recolecta
  • Logo del Observatorio I+D+i UPM
  • Logo de OpenCourseWare UPM