Safety study of transcranial static magnetic field stimulation (tSMS) of the human cortex

Oliviero, A. and Carrasco López, M.C. and Campolo, M. and Pérez Borrego, Y.A. and Soto León, V. and González Rosa, J.J. and Higuero, A.M. and Strange, Bryan A. and Abad Rodríguez, J. and Foffani, G. (2015). Safety study of transcranial static magnetic field stimulation (tSMS) of the human cortex. "Brain Stimulation", v. 8 (n. 3); pp. 481-485. ISSN 1935-861X. https://doi.org/10.1016/j.brs.2014.12.002.

Description

Title: Safety study of transcranial static magnetic field stimulation (tSMS) of the human cortex
Author/s:
  • Oliviero, A.
  • Carrasco López, M.C.
  • Campolo, M.
  • Pérez Borrego, Y.A.
  • Soto León, V.
  • González Rosa, J.J.
  • Higuero, A.M.
  • Strange, Bryan A.
  • Abad Rodríguez, J.
  • Foffani, G.
Item Type: Article
Título de Revista/Publicación: Brain Stimulation
Date: May 2015
ISSN: 1935-861X
Volume: 8
Subjects:
Freetext Keywords: NIBS; Repetitive transcranial magnetic stimulation (rTMS); Safety; Transcranial static magnetic field stimulation (tSMS); Neuron-specific enolase; S100
Faculty: E.T.S.I. Telecomunicación (UPM)
Department: Tecnología Fotónica y Bioingeniería
Creative Commons Licenses: Recognition - No derivative works - Non commercial

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Abstract

Transcranial static magnetic field stimulation (tSMS) in humans reduces cortical excitability. Objective: The objective of this study was to determine if prolonged tSMS (2 h) could be delivered safely in humans. Safety limits for this technique have not been described. Methods: tSMS was applied for 2 h with a cylindric magnet on the occiput of 17 healthy subjects. We assessed tSMS-related safety aspects at tissue level by measuring levels of neuron-specific enolase (NSE,a marker of neuronal damage) and S100 (a marker of glial reactivity and damage). We also included an evaluation of cognitive side effects by using a battery of visuomotor and cognitive tests. Results: tSMS did not induce any significant increase in NSE or S100. No cognitive alteration was detected. Conclusions: Our data indicate that the application of tSMS is safe in healthy human subjects, at least within these parameters

More information

Item ID: 41093
DC Identifier: http://oa.upm.es/41093/
OAI Identifier: oai:oa.upm.es:41093
DOI: 10.1016/j.brs.2014.12.002
Official URL: http://www.sciencedirect.com/science/article/pii/S1935861X14004021
Deposited by: Memoria Investigacion
Deposited on: 25 Jun 2016 11:42
Last Modified: 25 Jun 2016 11:42
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