Cita
Oliviero, A.; Carrasco López, M.C.; Campolo, M.; Pérez Borrego, Y.A.; Soto León, V.; González Rosa, J.J.; Higuero, A.M.; Strange, Bryan A.; Abad Rodríguez, J. y Foffani, G.
(2015).
Safety study of transcranial static magnetic field stimulation (tSMS) of the human cortex.
"Brain Stimulation", v. 8
(n. 3);
pp. 481-485.
ISSN 1935-861X.
https://doi.org/10.1016/j.brs.2014.12.002.
Resumen
Transcranial static magnetic field stimulation (tSMS) in humans reduces cortical excitability. Objective: The objective of this study was to determine if prolonged tSMS (2 h) could be delivered safely in humans. Safety limits for this technique have not been described.
Methods: tSMS was applied for 2 h with a cylindric magnet on the occiput of 17 healthy subjects. We assessed tSMS-related safety aspects at tissue level by measuring levels of neuron-specific enolase (NSE,a marker of neuronal damage) and S100 (a marker of glial reactivity and damage). We also included an evaluation of cognitive side effects by using a battery of visuomotor and cognitive tests. Results: tSMS did not induce any significant increase in NSE or S100. No cognitive alteration was detected. Conclusions: Our data indicate that the application of tSMS is safe in healthy human subjects, at least within these parameters
