Citation
García, Oscar and Moreno Arrones, Natalia and Bravo Cuesta, Andrés and Gutiérrez, Ana and Alou Cervera, Pedro and Oliver Ramírez, Jesús Angel and Cobos Márquez, José Antonio and Uceda Antolín, Javier and Aznar, Elena and Martínez Mañez, Ramón and Sánchez, Cristina and Casanova, Oscar E. and Serrano, José Javier and Pozo Guerrero, Francisco del
(2015).
Development and testing of a new instrument for researching on cancer treatment technologies based on magnetic hyperthermia.
"IEEE Journal of Emerging and Selected Topics in Power Electronics", v. 4
(n. 1);
pp. 243-251.
ISSN 2168-6777.
https://doi.org/10.1109/JESTPE.2015.2479092.
Abstract
A power electronics circuit allows the generation of high-frequency magnetic field that can be used to increase the temperature of cancer cells previously invaded with the magnetic nanoparticles. The circuit designed for this purpose is a high-frequency phase-shift inverter implemented with SiC devices and natural zero voltage switching. The inductive load has been optimized to increase as much as possible the magnetic field at the center of it considering the physical restrictions. Into this inductor, an adiabatic probe filled with nanoparticles is placed being the main objective to increase its temperature. The control of the inverter has been designed in such a way that it is easy to try waveforms different from the classical sine waves to see its effect on the temperature of the sample. Although the research is in one of the early stages, the first conclusions about the optimal frequency and field have been obtained showing that this technique could be a real option in the future.
