Development and testing of a new instrument for researching on cancer treatment technologies based on magnetic hyperthermia

García, Oscar; Moreno Arrones, Natalia; Bravo Cuesta, Andrés; Gutiérrez, Ana; Alou Cervera, Pedro; Oliver Ramírez, Jesús Angel; Cobos Márquez, José Antonio; Uceda Antolín, Javier; Aznar, Elena; Martínez Mañez, Ramón; Sánchez, Cristina; Casanova, Oscar E.; Serrano, José Javier y Pozo Guerrero, Francisco del (2015). Development and testing of a new instrument for researching on cancer treatment technologies based on magnetic hyperthermia. "IEEE Journal of Emerging and Selected Topics in Power Electronics", v. 4 (n. 1); pp. 243-251. ISSN 2168-6777. https://doi.org/10.1109/JESTPE.2015.2479092.

Descripción

Título: Development and testing of a new instrument for researching on cancer treatment technologies based on magnetic hyperthermia
Autor/es:
  • García, Oscar
  • Moreno Arrones, Natalia
  • Bravo Cuesta, Andrés
  • Gutiérrez, Ana
  • Alou Cervera, Pedro
  • Oliver Ramírez, Jesús Angel
  • Cobos Márquez, José Antonio
  • Uceda Antolín, Javier
  • Aznar, Elena
  • Martínez Mañez, Ramón
  • Sánchez, Cristina
  • Casanova, Oscar E.
  • Serrano, José Javier
  • Pozo Guerrero, Francisco del
Tipo de Documento: Artículo
Título de Revista/Publicación: IEEE Journal of Emerging and Selected Topics in Power Electronics
Fecha: Septiembre 2015
Volumen: 4
Materias:
Palabras Clave Informales: Cancer treatment, magnetic hyperthermia, nanomaterials, PWM Inverter
Escuela: E.T.S.I. Telecomunicación (UPM)
Departamento: Tecnología Fotónica y Bioingeniería
Licencias Creative Commons: Reconocimiento - Sin obra derivada - No comercial

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Resumen

A power electronics circuit allows the generation of high-frequency magnetic field that can be used to increase the temperature of cancer cells previously invaded with the magnetic nanoparticles. The circuit designed for this purpose is a high-frequency phase-shift inverter implemented with SiC devices and natural zero voltage switching. The inductive load has been optimized to increase as much as possible the magnetic field at the center of it considering the physical restrictions. Into this inductor, an adiabatic probe filled with nanoparticles is placed being the main objective to increase its temperature. The control of the inverter has been designed in such a way that it is easy to try waveforms different from the classical sine waves to see its effect on the temperature of the sample. Although the research is in one of the early stages, the first conclusions about the optimal frequency and field have been obtained showing that this technique could be a real option in the future.

Más información

ID de Registro: 41218
Identificador DC: http://oa.upm.es/41218/
Identificador OAI: oai:oa.upm.es:41218
Identificador DOI: 10.1109/JESTPE.2015.2479092
URL Oficial: http://ieeexplore.ieee.org/xpl/articleDetails.jsp?reload=true&arnumber=7268836
Depositado por: Memoria Investigacion
Depositado el: 29 Jun 2016 19:18
Ultima Modificación: 29 Jun 2016 19:18
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